MXD1 and CD2

Number of citations of the paper that reports this interaction (PMID 11602341)
43

Data Source:
HPRD (in vitro, in vivo)

		MXD1	CD2
Gene Name		MAX dimerization protein 1	CD2 molecule
Image
Gene Ontology Annotations	Cellular Component	Nucleus	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction External Side Of Plasma Membrane Cytoplasmic Side Of Plasma Membrane Cell Surface Anchored Component Of Plasma Membrane
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Transcription Corepressor Activity Protein Dimerization Activity	Receptor Activity Receptor Binding Protein Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Multicellular Organismal Development Cell Proliferation	Membrane Raft Polarization Apoptotic Process Cell Surface Receptor Signaling Pathway Blood Coagulation Single Organismal Cell-cell Adhesion Natural Killer Cell Activation Positive Regulation Of Myeloid Dendritic Cell Activation Positive Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion T Cell Activation Regulation Of T Cell Differentiation Leukocyte Migration Positive Regulation Of Interferon-gamma Secretion Positive Regulation Of Interleukin-8 Secretion
Pathways			Cell surface interactions at the vascular wall
Drugs			Alefacept Alpha-D-Mannose
Diseases
GWAS
Protein-Protein Interactions		18 interactors: AKT1 APP CD2 HDAC1 HDAC2 MAX MLX MYC MYCL MYCN PML PRAM1 RPS6KA1 RPS6KB1 SAP30 SIN3A SIN3B SMC3	19 interactors: CD247 CD2AP CD2BP2 CD4 CD48 CD5 CD53 CD58 CD59 FYN LCK LGALS1 LINC00311 LYAR MXD1 PSTPIP1 PTPRC SH3KBP1 SP1
Entrez ID		4084	914
HPRD ID		02487	01750
Ensembl ID		ENSG00000059728	ENSG00000116824
Uniprot IDs		B7ZLI7 Q05195	P06729 Q53F96
PDB IDs		1E91 1G1E 1NLW 1PD7 1S5Q	1CDB 1GYA 1HNF 1L2Z 1QA9 2J6O 2J7I
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Response To Wounding Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Histone Deacetylation Negative Regulation Of Gene Expression Cellular Response To Growth Factor Stimulus Negative Regulation Of Biosynthetic Process Anatomical Structure Development Protein Deacetylation Response To Growth Factor Regulation Of Metabolic Process Apoptotic Process Positive Regulation Of Cellular Metabolic Process Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression, Epigenetic Cell Death Positive Regulation Of Macromolecule Biosynthetic Process Death Response To Stress Regulation Of Cell Death Positive Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Blood Coagulation Regulation Of Cell Differentiation Hemostasis Negative Regulation Of Nucleic Acid-templated Transcription Developmental Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Organ Development Tissue Development Regulation Of Translation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organic Substance Negative Regulation Of Apoptotic Process Positive Regulation Of Proteolysis Negative Regulation Of Programmed Cell Death Regulation Of Body Fluid Levels System Development	Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of T Cell Activation T Cell Costimulation Positive Regulation Of Cell Activation Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Cell Activation Immune System Process Regulation Of Defense Response To Virus By Virus Regulation Of Cell Adhesion T Cell Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Immune System Process Defense Response Regulation Of Defense Response To Virus Innate Immune Response Cell Migration Locomotion Regulation Of Immune System Process Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response Cell Motility Signal Transduction Cellular Response To Stimulus Immune Response-regulating Cell Surface Receptor Signaling Pathway Cell Activation Response To Wounding Signaling Lymphocyte Activation Response To Stimulus Cell Communication Blood Coagulation Hemostasis Immune Response-regulating Signaling Pathway Positive Regulation Of Gamma-delta T Cell Differentiation Leukocyte Activation Leukocyte Migration Regulation Of Immune Response Lymphocyte Differentiation Positive Regulation Of Gamma-delta T Cell Activation Single Organismal Cell-cell Adhesion Response To Stress Viral Process T Cell Aggregation T Cell Activation Regulation Of Gamma-delta T Cell Differentiation Lymphocyte Aggregation
Tagcloud ?		achievable bio boolean broader bromoindirubin deeper easily ets extrapolation fr180204 gsk3 implement jun mathematical modelled modelling oxime pharmacology programme prove qpcr repression rescued sp3 stimulatory su6656 telomerase tert unstable	2c4 assign b10 b3 b9 complementation crossed crosses crossing facs gbp guanylate hlas hybrids ifn jak1 oas oligoadenylate pairwise permitted responsiveness restore rounds submitted synthetase u3 u4 unresponsive unresponsiveness
Tagcloud (Difference) ?		achievable bio boolean broader bromoindirubin deeper easily ets extrapolation fr180204 gsk3 implement jun mathematical modelled modelling oxime pharmacology programme prove qpcr repression rescued sp3 stimulatory su6656 telomerase tert unstable	2c4 assign b10 b3 b9 complementation crossed crosses crossing facs gbp guanylate hlas hybrids ifn jak1 oas oligoadenylate pairwise permitted responsiveness restore rounds submitted synthetase u3 u4 unresponsive unresponsiveness
Tagcloud (Intersection) ?