MXD1 and MYCL

Number of citations of the paper that reports this interaction (PMID 11602341)
43

Data Source:
HPRD (in vitro, in vivo)

		MXD1	MYCL
Gene Name		MAX dimerization protein 1	v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Transcription Corepressor Activity Protein Dimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Multicellular Organismal Development Cell Proliferation	Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: AKT1 APP CD2 HDAC1 HDAC2 MAX MLX MYC MYCL MYCN PML PRAM1 RPS6KA1 RPS6KB1 SAP30 SIN3A SIN3B SMC3	2 interactors: MAX MXD1
Entrez ID		4084	4610
HPRD ID		02487	01279
Ensembl ID		ENSG00000059728	ENSG00000116990
Uniprot IDs		B7ZLI7 Q05195	B4DJH2 P12524
PDB IDs		1E91 1G1E 1NLW 1PD7 1S5Q
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Response To Wounding Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Histone Deacetylation Negative Regulation Of Gene Expression Cellular Response To Growth Factor Stimulus Negative Regulation Of Biosynthetic Process Anatomical Structure Development Protein Deacetylation Response To Growth Factor Regulation Of Metabolic Process Apoptotic Process Positive Regulation Of Cellular Metabolic Process Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression, Epigenetic Cell Death Positive Regulation Of Macromolecule Biosynthetic Process Death Response To Stress Regulation Of Cell Death Positive Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Blood Coagulation Regulation Of Cell Differentiation Hemostasis Negative Regulation Of Nucleic Acid-templated Transcription Developmental Process Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Organ Development Tissue Development Regulation Of Translation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organic Substance Negative Regulation Of Apoptotic Process Positive Regulation Of Proteolysis Negative Regulation Of Programmed Cell Death Regulation Of Body Fluid Levels System Development
Tagcloud ?		achievable bio boolean broader bromoindirubin deeper easily ets extrapolation fr180204 gsk3 implement jun mathematical modelled modelling oxime pharmacology programme prove qpcr repression rescued sp3 stimulatory su6656 telomerase tert unstable	amenable barr colonies cotransfection ebna1 episomal episome epstein erythroblasts gently hesc illustrates imef imefs ipsc ipscs klf4 lin28a manuscript nonintegrating nontransmissible nucleofection oct4 phlebotomy plasmids plated reprogrammed reprogramming soon
Tagcloud (Difference) ?		achievable bio boolean broader bromoindirubin deeper easily ets extrapolation fr180204 gsk3 implement jun mathematical modelled modelling oxime pharmacology programme prove qpcr repression rescued sp3 stimulatory su6656 telomerase tert unstable	amenable barr colonies cotransfection ebna1 episomal episome epstein erythroblasts gently hesc illustrates imef imefs ipsc ipscs klf4 lin28a manuscript nonintegrating nontransmissible nucleofection oct4 phlebotomy plasmids plated reprogrammed reprogramming soon
Tagcloud (Intersection) ?