MIR92A2 and CSTF1

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR92A2	CSTF1
Description		microRNA 92a-2	cleavage stimulation factor subunit 1
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex	Nucleus Nucleoplasm MRNA Cleavage Stimulating Factor Complex
	Molecular Function		RNA Binding Protein Binding
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing	MRNA Processing MRNA 3'-end Processing
Pathways			mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS			Cognitive decline (age-related) ( 28078323)
Interacting Genes		88 interacting genes: ADARB1 AIMP2 AQR C1QBP CELF1 CPSF1 CPSF2 CPSF3 CPSF4 CSTF1 CSTF2 CSTF3 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FIP1L1 FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBM14 RBM4 RBMS1 RBMS2 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2B TRIM25 UPF1 UTP20 WDR33 YBX1 YBX3 ZC3H7A ZNF346	12 interacting genes: BARD1 BRCA1 CSTF3 H2AC20 MIR140 MIR206 MIR92A2 MIRLET7A3 MIRLET7I POLR2A VCP WEE2-AS1
Entrez ID		407049	1477
HPRD ID			02653
Ensembl ID		ENSG00000284538	ENSG00000101138
Uniprot IDs			Q05048
PDB IDs			6B3X
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Processing RNA Metabolic Process Nucleic Acid Binding Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing Macromolecule Metabolic Process Nucleus MRNA Binding Nucleoplasm Regulation Of MRNA Metabolic Process Ribonucleoprotein Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Aminoacyl-tRNA Synthetase Multienzyme Complex Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA Binding Catalytic Step 2 Spliceosome Cytoplasmic Stress Granule Spliceosomal Complex Regulation Of Translation Negative Regulation Of MRNA Metabolic Process MRNA Cleavage And Polyadenylation Specificity Factor Complex Regulation Of MRNA Processing Regulation Of RNA Stability TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Translation TRNA Aminoacylation Regulation Of MRNA Stability Ligase Activity Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization RNA 3'-end Processing MRNA Stabilization Positive Regulation Of Cytoplasmic Translation TRNA Metabolic Process MiRNA Processing Positive Regulation Of Gene Expression CRD-mediated MRNA Stabilization Nucleolus Regulation Of Gene Expression MRNA 5'-UTR Binding	RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Histone H2AK127 Ubiquitin Ligase Activity Histone H2AK129 Ubiquitin Ligase Activity BRCA1-BARD1 Complex BRCA1-B Complex Negative Regulation Of Gene Expression Nuclear Ubiquitin Ligase Complex BRCA1-C Complex MRNA Base-pairing Post-transcriptional Repressor Activity BRCA1-A Complex Ubiquitin-modified Histone Reader Activity Post-transcriptional Regulation Of Gene Expression DNA Strand Resection Involved In Replication Fork Processing Negative Regulation Of Macromolecule Metabolic Process MRNA 3'-UTR Binding Regulation Of DNA Damage Checkpoint Negative Regulation Of Metabolic Process Protein K6-linked Ubiquitination Negative Regulation Of Macromolecule Biosynthetic Process Postreplication Repair Homologous Recombination Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Macromolecule Metabolic Process Positive Regulation Of Catabolic Process Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Interleukin-6 Production Mitotic G2/M Transition Checkpoint Negative Regulation Of MRNA 3'-end Processing Flavin Adenine Dinucleotide Catabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Lipid Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Ubiquitin Protein Ligase Binding Negative Regulation Of Cell Cycle G2/M Phase Transition Cellular Response To Ionizing Radiation Regulation Of MRNA Metabolic Process MRNA Cleavage Stimulating Factor Complex VCP-NSFL1C Complex Endoplasmic Reticulum Stress-induced Pre-emptive Quality Control Positive Regulation Of Protein K63-linked Deubiquitination Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Intracellular Signal Transduction RNA-directed RNA Polymerase Activity
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