MIR92A2 and CPSF4

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR92A2	CPSF4
Description		microRNA 92a-2	cleavage and polyadenylation specific factor 4
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function		Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing	MRNA Processing
Pathways			Transport of Mature mRNA Derived from an Intronless Transcript Inhibition of Host mRNA Processing and RNA Silencing tRNA processing in the nucleus mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS			Diffuse cutaneous systemic sclerosis ( 29293537) Facial emotion recognition (sad faces) ( 28608620) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) Serum metabolite levels ( 23093944) Tacrolimus trough concentration in kidney transplant patients ( 29160300)
Interacting Genes		88 interacting genes: ADARB1 AIMP2 AQR C1QBP CELF1 CPSF1 CPSF2 CPSF3 CPSF4 CSTF1 CSTF2 CSTF3 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FIP1L1 FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBM14 RBM4 RBMS1 RBMS2 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2B TRIM25 UPF1 UTP20 WDR33 YBX1 YBX3 ZC3H7A ZNF346	10 interacting genes: CREBBP FIP1L1 MARK3 MEOX2 MID2 MIR19A MIR19B1 MIR92A2 MYOG SLC12A9
Entrez ID		407049	10898
HPRD ID			04338
Ensembl ID		ENSG00000284538	ENSG00000160917
Uniprot IDs			B7Z7B0 O95639
PDB IDs			2D9N 2RHK 6DNH 6FUW 6URG 6URO 7K95 7ZYH 8E3I 8E3Q 8R8R
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Processing RNA Metabolic Process Nucleic Acid Binding Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing Macromolecule Metabolic Process Nucleus MRNA Binding Nucleoplasm Regulation Of MRNA Metabolic Process Ribonucleoprotein Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Aminoacyl-tRNA Synthetase Multienzyme Complex Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA Binding Catalytic Step 2 Spliceosome Cytoplasmic Stress Granule Spliceosomal Complex Regulation Of Translation Negative Regulation Of MRNA Metabolic Process MRNA Cleavage And Polyadenylation Specificity Factor Complex Regulation Of MRNA Processing Regulation Of RNA Stability TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Translation TRNA Aminoacylation Regulation Of MRNA Stability Ligase Activity Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization RNA 3'-end Processing MRNA Stabilization Positive Regulation Of Cytoplasmic Translation TRNA Metabolic Process MiRNA Processing Positive Regulation Of Gene Expression CRD-mediated MRNA Stabilization Nucleolus Regulation Of Gene Expression MRNA 5'-UTR Binding	Positive Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of Cardiac Epithelial To Mesenchymal Transition Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Extracellular Matrix Assembly Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development RISC Complex Cellular Response To Bacterial Lipopeptide Negative Regulation Of Matrix Metallopeptidase Secretion Response To Bacterial Lipoprotein Negative Regulation Of Fibroblast Migration Muscle Cell Fate Commitment MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Extracellular Matrix Assembly Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Muscle Cell Differentiation Negative Regulation Of Extracellular Matrix Organization Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Inflammatory Response To Antigenic Stimulus Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Heart Growth Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Striated Muscle Cell Apoptotic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Protein Localization Regulation Of Fibroblast Migration Tau Protein Binding Negative Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Muscle System Process Positive Regulation Of Organ Growth Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Interleukin-6 Production Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Muscle Cell Apoptotic Process MRNA Base-pairing Post-transcriptional Repressor Activity Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Reverse Cholesterol Transport Negative Regulation Of Apolipoprotein A-I-mediated Signaling Pathway Skeletal Muscle Tissue Development Regulation Of Heart Growth Regulation Of Extracellular Matrix Organization
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