MIR92A2 and TAF15

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR92A2	TAF15
Description		microRNA 92a-2	TATA-box binding protein associated factor 15
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function		Nucleic Acid Binding DNA Binding Transcription Coregulator Activity RNA Binding MRNA 3'-UTR Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	MiRNA-mediated Post-transcriptional Gene Silencing	Regulation Of DNA-templated Transcription RNA Splicing Gene Expression Positive Regulation Of DNA-templated Transcription MRNA Stabilization
Pathways			HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases			Extraskeletal myxoid chondrosarcoma
GWAS			Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		88 interacting genes: ADARB1 AIMP2 AQR C1QBP CELF1 CPSF1 CPSF2 CPSF3 CPSF4 CSTF1 CSTF2 CSTF3 DARS1 DDX1 DDX21 DDX3X DHX36 DHX37 EDC4 EIF2AK2 EPRS1 FAM98A FIP1L1 FUS HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 NOL6 NONO PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PUM2 PURA QARS1 RARS1 RBM14 RBM4 RBMS1 RBMS2 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 SUGP2 SYMPK SYNCRIP TAF15 TRA2B TRIM25 UPF1 UTP20 WDR33 YBX1 YBX3 ZC3H7A ZNF346	95 interacting genes: ARID1A CACNA1A H2AC20 H3-4 H3C1 H4C14 ITCH MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I OGT POLR2C POLR2E POLR2G SAFB SF1 SMARCA4 SMARCC1 SMARCC2 TAF1 TAF12 TAF13 TAF5 TAF7 YWHAG ZNF384
Entrez ID		407049	8148
HPRD ID			09031
Ensembl ID		ENSG00000284538	ENSG00000270647
Uniprot IDs			Q92804
PDB IDs			2MMY 8ONS
Enriched GO Terms of Interacting Partners?		RNA Binding RNA Processing RNA Metabolic Process Nucleic Acid Binding Nucleic Acid Metabolic Process MRNA Processing MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Splicing Macromolecule Metabolic Process Nucleus MRNA Binding Nucleoplasm Regulation Of MRNA Metabolic Process Ribonucleoprotein Complex MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Aminoacyl-tRNA Synthetase Multienzyme Complex Post-transcriptional Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA Binding Catalytic Step 2 Spliceosome Cytoplasmic Stress Granule Spliceosomal Complex Regulation Of Translation Negative Regulation Of MRNA Metabolic Process MRNA Cleavage And Polyadenylation Specificity Factor Complex Regulation Of MRNA Processing Regulation Of RNA Stability TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Translation TRNA Aminoacylation Regulation Of MRNA Stability Ligase Activity Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization RNA 3'-end Processing MRNA Stabilization Positive Regulation Of Cytoplasmic Translation TRNA Metabolic Process MiRNA Processing Positive Regulation Of Gene Expression CRD-mediated MRNA Stabilization Nucleolus Regulation Of Gene Expression MRNA 5'-UTR Binding	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Regulation Of Gene Expression Extracellular Vesicle Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Positive Regulation Of MRNA Catabolic Process MRNA Destabilization RNA Destabilization Negative Regulation Of Cytokine Production Negative Regulation Of Cell Migration Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Regulation Of Translation Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Protein Metabolic Process Negative Regulation Of Multicellular Organismal Process Negative Regulation Of Developmental Process Regulation Of MRNA Stability Regulation Of RNA Stability Negative Regulation Of Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Signaling Negative Regulation Of Cell Communication Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of MRNA Metabolic Process Regulation Of Endothelial Cell Migration Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Blood Vessel Endothelial Cell Migration
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