MIR128-2 and AQR

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR128-2	AQR
Description		microRNA 128-2	aquarius intron-binding spliceosomal factor
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex	Nucleus Nucleoplasm Spliceosomal Complex Membrane U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function		Nucleotide Binding RNA Binding RNA Helicase Activity Single-stranded RNA Binding MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity 3'-5' RNA Helicase Activity
	Biological Process		MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways			Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Urinary sodium excretion ( 31409800)
Interacting Genes		98 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CPSF1 CPSF6 CPSF7 CSTF3 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PTBP1 PTCD3 PUF60 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RTCA RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR	40 interacting genes: MIR1-1 MIR106A MIR106B MIR107 MIR128-2 MIR145 MIR15B MIR199A2 MIR19B1 MIR19B2 MIR200B MIR200C MIR205 MIR206 MIR20B MIR214 MIR221 MIR222 MIR25 MIR29A MIR31 MIR34A MIR34B MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR92A2 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7D MIRLET7E MIRLET7G MIRLET7I PQBP1 RBM22 RBM4 WDR77
Entrez ID		406916	9716
HPRD ID			12468
Ensembl ID		ENSG00000207625	ENSG00000021776
Uniprot IDs			O60306
PDB IDs			4PJ3 5MQF 5XJC 5YZG 5Z56 5Z57 6FF7 6ICZ 6ID0 6ID1 6QDV 7A5P 7ABI 7W59 7W5A 7W5B 8C6J 8CH6 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8RO2 9FMD
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Nucleus Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Post-transcriptional Regulation Of Gene Expression Nucleoplasm Ribonucleoprotein Complex Cytoplasmic Stress Granule Regulation Of Translation Spliceosomal Complex Catalytic Step 2 Spliceosome MiRNA Binding MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Translation Regulation Of MRNA Stability Ligase Activity MRNA Stabilization Regulation Of Macromolecule Metabolic Process Regulation Of RNA Stability MRNA Cleavage And Polyadenylation Specificity Factor Complex Positive Regulation Of Cytoplasmic Translation Regulation Of Primary Metabolic Process TRNA Metabolic Process Paraspeckles Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway CRD-mediated MRNA Stabilization	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization Extracellular Vesicle Negative Regulation Of Metabolic Process Negative Regulation Of Translation Positive Regulation Of MRNA Metabolic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Destabilization Regulation Of Macromolecule Metabolic Process RNA Destabilization Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Cytokine Production Regulation Of Metabolic Process Regulation Of MRNA Stability Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration Regulation Of Translation Regulation Of RNA Stability Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Protein Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Developmental Process Regulation Of Cytokine Production Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Multicellular Organismal Development Negative Regulation Of Developmental Process Regulation Of Muscle Cell Differentiation Negative Regulation Of Endothelial Cell Migration Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Signal Transduction
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