MIR128-2 and ATXN2L

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR128-2	ATXN2L
Description		microRNA 128-2	ataxin 2 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	RISC Complex	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane Nuclear Speck
	Molecular Function		RNA Binding MRNA Binding Protein Binding Cadherin Binding
	Biological Process		MRNA Metabolic Process Stress Granule Assembly
Pathways
Drugs
Diseases
GWAS		Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Urinary sodium excretion ( 31409800)	Albumin-globulin ratio ( 29403010) Allergic disease (asthma, hay fever or eczema) ( 29679657) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body fat percentage ( 26833246) Body mass index ( 20935630 28448500 28552196) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Brain morphology (MOSTest) ( 32665545) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Crohn's disease ( 28067908) Educational attainment ( 23722424 25201988) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Extremely high intelligence ( 29520040) Hand grip strength ( 29691431) Inflammatory bowel disease ( 28067908) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Lamb consumption ( 32066663) Left-handedness ( 32989287) Pediatric autoimmune diseases ( 26301688) Waist circumference ( 28552196) Weight ( 28552196)
Interacting Genes		98 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CPSF1 CPSF6 CPSF7 CSTF3 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PTBP1 PTCD3 PUF60 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RTCA RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR	42 interacting genes: ATXN1 BOLL CEBPA EPOR HADHA HOXA1 KRTAP12-4 MIR1-1 MIR10B MIR128-1 MIR128-2 MIR15B MIR16-2 MIR17 MIR19A MIR200C MIR205 MIR20B MIR21 MIR214 MIR25 MIR31 MIR34A MIR34B MIR363 MIR7-1 MIR7-2 MIR7-3 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MPL OGT
Entrez ID		406916	11273
HPRD ID			06394
Ensembl ID		ENSG00000207625	ENSG00000168488
Uniprot IDs			H3BUF6 Q8WWM7
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Nucleus Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Post-transcriptional Regulation Of Gene Expression Nucleoplasm Ribonucleoprotein Complex Cytoplasmic Stress Granule Regulation Of Translation Spliceosomal Complex Catalytic Step 2 Spliceosome MiRNA Binding MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Translation Regulation Of MRNA Stability Ligase Activity MRNA Stabilization Regulation Of Macromolecule Metabolic Process Regulation Of RNA Stability MRNA Cleavage And Polyadenylation Specificity Factor Complex Positive Regulation Of Cytoplasmic Translation Regulation Of Primary Metabolic Process TRNA Metabolic Process Paraspeckles Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway CRD-mediated MRNA Stabilization	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Metabolic Process Extracellular Vesicle MRNA Destabilization Negative Regulation Of Translation RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability Positive Regulation Of MRNA Metabolic Process Regulation Of RNA Stability Negative Regulation Of Cell Migration Regulation Of Translation Negative Regulation Of Cytokine Production Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Motility Regulation Of Macromolecule Metabolic Process Negative Regulation Of Locomotion Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Extracellular Space Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development Regulation Of Metabolic Process Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Connective Tissue Replacement Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Protein Metabolic Process Regulation Of Endothelial Cell Proliferation Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Connective Tissue Replacement Negative Regulation Of Signal Transduction
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