MIR128-2 and PTCD3

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR128-2	PTCD3
Description		microRNA 128-2	pentatricopeptide repeat domain 3
Image		No pdb structure
GO Annotations	Cellular Component	RISC Complex	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Mitochondrial Small Ribosomal Subunit Cytosol Ribosome Plasma Membrane Ribonucleoprotein Complex
	Molecular Function		RNA Binding Protein Binding RRNA Binding Ribosomal Small Subunit Binding
	Biological Process		Regulation Of Translation Mitochondrial Translation
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Urinary sodium excretion ( 31409800)	Diastolic blood pressure ( 27841878) Facial emotion recognition (sad faces) ( 28608620) Pulse pressure ( 27841878) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Systolic blood pressure ( 27841878)
Interacting Genes		98 interacting genes: AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CPSF1 CPSF6 CPSF7 CSTF3 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PLOD1 PTBP1 PTCD3 PUF60 PUM1 PUM2 PURA PURB QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RTCA RTCB SART3 SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SUGP2 SYMPK SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZFR	22 interacting genes: ATF4 BIRC7 HGS IFITM2 LNX2 LUC7L2 MIR128-2 MIR18B MIR200B MIR200C MIR205 MIR21 MIR214 MIR34B MIR34C MIR363 MIRLET7A2 MIRLET7F2 MIRLET7G MT-RNR1 TBPL1 UBE3A
Entrez ID		406916	55037
HPRD ID			08631
Ensembl ID		ENSG00000207625	ENSG00000132300
Uniprot IDs			Q96EY7
PDB IDs			3J9M 6NU2 6NU3 6RW4 6RW5 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5I 7A5K 7L08 7OG4 7P2E 7PNX 7PNY 7PNZ 7PO0 7PO1 7PO2 7PO3 7QI4 7QI5 7QI6 8ANY 8CSP 8CSQ 8CSR 8CSS 8CST 8CSU 8K2A 8OIR 8OIS 8QRK 8QRL 8QRM 8QRN 8RRI 8XT0 8XT2
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process MRNA Binding Macromolecule Metabolic Process Nucleus Regulation Of MRNA Metabolic Process MRNA Splicing, Via Spliceosome Aminoacyl-tRNA Synthetase Multienzyme Complex RNA Splicing, Via Transesterification Reactions Regulation Of RNA Splicing Post-transcriptional Regulation Of Gene Expression Nucleoplasm Ribonucleoprotein Complex Cytoplasmic Stress Granule Regulation Of Translation Spliceosomal Complex Catalytic Step 2 Spliceosome MiRNA Binding MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity TRNA Aminoacylation Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Translation Regulation Of MRNA Stability Ligase Activity MRNA Stabilization Regulation Of Macromolecule Metabolic Process Regulation Of RNA Stability MRNA Cleavage And Polyadenylation Specificity Factor Complex Positive Regulation Of Cytoplasmic Translation Regulation Of Primary Metabolic Process TRNA Metabolic Process Paraspeckles Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway CRD-mediated MRNA Stabilization	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing RISC Complex Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding Negative Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Regulation Of Angiogenesis Regulation Of Vasculature Development MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Signal Transduction Negative Regulation Of Cell Communication Negative Regulation Of Signaling Negative Regulation Of Translation Positive Regulation Of Cardiac Muscle Hypertrophy MiRNA-mediated Gene Silencing By MRNA Destabilization Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Connective Tissue Replacement Regulation Of Multicellular Organismal Development Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Connective Tissue Replacement Regulation Of Osteoblast Differentiation Negative Regulation Of Interleukin-33 Production Negative Regulation Of Endothelial Cell Migration Regulation Of Cardiac Muscle Hypertrophy Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Tissue Remodeling Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Metabolic Process Negative Regulation Of Multicellular Organismal Process Regulation Of Anatomical Structure Morphogenesis MRNA Destabilization RNA Destabilization Regulation Of Translation Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Developmental Process Regulation Of Muscle System Process Negative Regulation Of Cell Population Proliferation Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Protein Metabolic Process
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