LOXL1 and FBLN5

Number of citations of the paper that reports this interaction (PMID 14745449)
107

Data Source:
BioGRID (pull down, affinity chromatography technology, two hybrid)
HPRD (in vitro, two hybrid, in vivo)

		LOXL1	FBLN5
Gene Name		lysyl oxidase-like 1	fibulin 5
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Extracellular Region Basement Membrane Extracellular Space Extracellular Matrix	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Space Extracellular Matrix Extracellular Vesicular Exosome Elastic Fiber
	Molecular Function	Copper Ion Binding Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, Oxygen As Acceptor	Integrin Binding Calcium Ion Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity
	Biological Process	Protein Deamination Extracellular Matrix Organization Response To Lipopolysaccharide Aorta Development Oxidation-reduction Process	Regulation Of Cell Growth Cell-matrix Adhesion Extracellular Matrix Organization Protein Localization To Cell Surface Secretion Elastic Fiber Assembly Regulation Of Removal Of Superoxide Radicals
Pathways		Collagen formation Crosslinking of collagen fibrils Elastic fibre formation Assembly of collagen fibrils and other multimeric structures	Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS		Aortic root size ( 19584346) Glaucoma (exfoliation) ( 17690259) Height ( 23563607)	Height ( 18391951)
Protein-Protein Interactions		3 interactors: ATXN1 ELN FBLN5	7 interactors: ATN1 GFI1B LOXL1 LPA PAXIP1 SOD3 TOP3B
Entrez ID		4016	10516
HPRD ID		08861	05204
Ensembl ID		ENSG00000129038	ENSG00000140092
Uniprot IDs		Q08397	Q9UBX5
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Elastic Fiber Assembly Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Removal Of Superoxide Radicals Stress Fiber Assembly Extracellular Matrix Assembly Protein Localization To Cell Surface	Regulation Of Histone H3-K4 Methylation Regulation Of Histone Methylation Positive Regulation Of Histone H3-K36 Methylation Protein Deamination Regulation Of Histone Modification Regulation Of Chromosome Organization
Tagcloud ?		addressed anterior aqueous capsule cornea deposited elastic elucidation exfoliation extensively fibers fibrillar glaucoma humor immersed intraocular ipe iris lens material meshwork pigment pseudoexfoliation reaches scarce trabecular ultrastructural underneath xfm	5g acetylcholine ach acta2 anxa2 aortic contractile contraction desmin ecm elasticity glycoproteins herbal inductive isobaric itraq kcl pe phenylephrine proteome reasoning stabilizing tag tcm thoracic thrombotic tianma vasodilatory vasorelaxation
Tagcloud (Difference) ?		addressed anterior aqueous capsule cornea deposited elastic elucidation exfoliation extensively fibers fibrillar glaucoma humor immersed intraocular ipe iris lens material meshwork pigment pseudoexfoliation reaches scarce trabecular ultrastructural underneath xfm	5g acetylcholine ach acta2 anxa2 aortic contractile contraction desmin ecm elasticity glycoproteins herbal inductive isobaric itraq kcl pe phenylephrine proteome reasoning stabilizing tag tcm thoracic thrombotic tianma vasodilatory vasorelaxation
Tagcloud (Intersection) ?