LOXL1

Gene Name		lysyl oxidase-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Extracellular Region Basement Membrane Extracellular Space Extracellular Matrix
	Molecular Function	Copper Ion Binding Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, Oxygen As Acceptor
	Biological Process	Protein Deamination Extracellular Matrix Organization Response To Lipopolysaccharide Aorta Development Oxidation-reduction Process
Pathways		Collagen formation Crosslinking of collagen fibrils Elastic fibre formation Assembly of collagen fibrils and other multimeric structures
Drugs
Diseases
GWAS		Aortic root size ( 19584346) Glaucoma (exfoliation) ( 17690259) Height ( 23563607)
Protein-protein Interactions		3 interactors: ATXN1 ELN FBLN5
Entrez ID		4016
HPRD ID		08861
Ensembl ID		ENSG00000129038
Uniprot IDs		Q08397
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Elastic Fiber Assembly Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Removal Of Superoxide Radicals Stress Fiber Assembly Extracellular Matrix Assembly Protein Localization To Cell Surface
Tagcloud ?		addressed anterior aqueous capsule cornea deposited elastic elucidation exfoliation extensively fibers fibrillar glaucoma humor immersed intraocular ipe iris lens material meshwork pigment pseudoexfoliation reaches scarce trabecular ultrastructural underneath xfm