CENPP and CCDC33

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		CENPP	CCDC33
Description		centromere protein P	coiled-coil domain containing 33
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Inner Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol	Peroxisome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Chromosome Segregation CENP-A Containing Chromatin Assembly
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		End-stage renal disease ( 29885931) HDL cholesterol levels ( 32203549) Height ( 28552196 31562340) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Bacterial meningitis ( 31092817) Coffee consumption (cups per day) ( 31837886) Craniofacial microsomia ( 26853712) Diastolic blood pressure ( 30224653) Diisocyanate-induced asthma ( 25918132) Hip circumference adjusted for BMI ( 34021172) Obesity-related traits ( 23251661) Systolic blood pressure ( 30578418)
Interacting Genes		26 interacting genes: AKAP19 ATP6V0D2 BACH2 CCDC33 CCDC85B CEP44 GOLGA2 HAUS1 KIAA1328 KLC3 LMNA MBD3 NHLH1 NTAQ1 PKNOX2 POLR3K RNF126 RPIA SERTAD3 STXBP1 SYCE1L TEX11 TOX2 USHBP1 ZNF341 ZNF765	159 interacting genes: ABCF3 ABLIM3 AIRIM ANKS1A AP1M1 APP ARHGEF6 ARIH2 ARMC7 ARNT2 ATOSB BCCIP BLK BLZF1 BYSL CABP2 CALCOCO2 CCDC102B CCDC57 CCDC6 CCDC85B CCHCR1 CCNH CDC23 CDCA7L CDKN2B CENPP CFAP206 CHCHD3 CINP CIRSR CRYBA2 CRYBA4 CTNNA3 DGCR6 DIP2A DVL2 DVL3 EAF1 EFEMP2 EHMT2 EMC2 EMD ESRRG EXOC8 FAM124A FAM161A FRS3 FXR2 GCC1 GPANK1 GPATCH2L GRN GYS1 HEXIM2 HGS HNRNPF HNRNPK HOOK2 HOXA1 HSF2BP IL16 ING5 ITGB1BP1 KANK2 KCTD19 KCTD9 KDM1A KHDRBS3 KIFC3 KLHL38 KXD1 L3MBTL2 LDOC1 LMO1 LMO2 LMO3 LNX1 MAGED1 MAGOHB MAPK9 MDFI MFAP1 MID2 MIPOL1 MISP MKRN3 MLH1 MOS NAB2 NCK2 NDOR1 NECAB2 NEFL NINL NME7 OSGIN1 OSTF1 PCSK5 PID1 PIK3R3 PIN1 PLA2G6 PLSCR1 PNMA1 PNMA2 POLR1C PPP2R3C PRKAA2 PRKAB2 PRPF31 PTGER3 PTK6 QARS1 RAD51D RAD54B RBMX RHOXF2 RNF6 SCNM1 SMAD3 SMARCB1 SMARCD1 SMYD1 SPAG5 SPG21 STK16 STX11 SYT17 TASOR2 TCEANC TGFB1 TMCC2 TNS2 TRAF2 TRIM23 TRIM37 TRIM42 TRIM59 TSC22D4 TSEN15 TSGA10 TTC19 TUFT1 TXK TXLNA UBASH3A UBQLN4 USHBP1 VPS52 WT1 YES1 ZBTB8A ZGPAT ZNF330 ZNF572 ZNF688 ZNF76 ZNRD2
Entrez ID		401541	80125
HPRD ID		17989	09959
Ensembl ID		ENSG00000188312	ENSG00000140481
Uniprot IDs		Q6IPU0	A0A1B0GV97 Q8N5R6
PDB IDs		7PB8 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?		Centrosome Cycle	Protein Binding Identical Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Nucleus Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleoplasm Cytoplasm Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Macromolecule Biosynthetic Process CD4 Receptor Binding Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Regulation Of Primary Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Neuron Maturation Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Speck Spliceosomal Complex Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Enzyme Binding
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