CENPP and SYCE1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CENPP	SYCE1L
Description		centromere protein P	synaptonemal complex central element protein 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Chromosome, Centromeric Region Inner Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol	Synaptonemal Complex Intermediate Filament Cytoskeleton
	Molecular Function	Protein Binding
	Biological Process	Chromosome Segregation CENP-A Containing Chromatin Assembly	Synaptonemal Complex Assembly Meiotic Cell Cycle Synaptonemal Complex Organization
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		End-stage renal disease ( 29885931) HDL cholesterol levels ( 32203549) Height ( 28552196 31562340) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		26 interacting genes: AKAP19 ATP6V0D2 BACH2 CCDC33 CCDC85B CEP44 GOLGA2 HAUS1 KIAA1328 KLC3 LMNA MBD3 NHLH1 NTAQ1 PKNOX2 POLR3K RNF126 RPIA SERTAD3 STXBP1 SYCE1L TEX11 TOX2 USHBP1 ZNF341 ZNF765	36 interacting genes: ALDH18A1 ANKRD36 ATF5 BFSP2 BOLL C1orf216 C22orf39 CALN1 CCDC146 CCDC196 CCHCR1 CENPP CST1 CYTH4 DPPA3 EPC1 FGA HSF2BP KCNIP2 KIAA1328 LCA5L LNX1 MED10 NOL4 NTAQ1 ODF1 OIP5 PFDN5 SCHIP1 SLC7A8 SMARCD1 SPHKAP SRSF10 TNNI1 TRAPPC13 ZNF526
Entrez ID		401541	100130958
HPRD ID		17989
Ensembl ID		ENSG00000188312	ENSG00000205078
Uniprot IDs		Q6IPU0	A8MT33
PDB IDs		7PB8 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH
Enriched GO Terms of Interacting Partners?		Centrosome Cycle
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