CENPP and CEP44

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CENPP	CEP44
Description		centromere protein P	centrosomal protein 44
Image
GO Annotations	Cellular Component	Chromosome, Centromeric Region Inner Kinetochore Nucleus Nucleoplasm Chromosome Nucleolus Cytosol	Spindle Pole Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Midbody Ciliary Basal Body
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding
	Biological Process	Chromosome Segregation CENP-A Containing Chromatin Assembly	Centrosome Cycle Centriole Replication Centriole-centriole Cohesion
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		End-stage renal disease ( 29885931) HDL cholesterol levels ( 32203549) Height ( 28552196 31562340) Malaria ( 31844061) Pulse pressure ( 30578418) Systolic blood pressure ( 30224653 30578418) Triglyceride levels ( 32203549) Urate levels ( 31578528) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		26 interacting genes: AKAP19 ATP6V0D2 BACH2 CCDC33 CCDC85B CEP44 GOLGA2 HAUS1 KIAA1328 KLC3 LMNA MBD3 NHLH1 NTAQ1 PKNOX2 POLR3K RNF126 RPIA SERTAD3 STXBP1 SYCE1L TEX11 TOX2 USHBP1 ZNF341 ZNF765	55 interacting genes: ABI2 ABI3 ANKRD11 AQP1 BEND7 BFSP2 BLOC1S6 BYSL CAB39 CBY2 CCDC116 CCDC146 CCDC185 CDC23 CENPP CEP57L1 CHIC2 DCTN2 DHX57 DIP2A ERAL1 FAM161A FAM74A4 FXR2 GNG11 H2AP HAUS1 ING5 KIAA0930 LINC02363 LMO1 LRRFIP1 MAPK9 MCRS1 MLLT6 MRFAP1L1 NAA10 PLEKHF2 POC1B POLR3C POP5 PSMD3 RBM15 RECK RNF8 SCNM1 TCEA2 TRIM41 TSGA10 TXLNA ZFYVE26 ZNF250 ZNF417 ZNF587 ZNF688
Entrez ID		401541	80817
HPRD ID		17989	13885
Ensembl ID		ENSG00000188312	ENSG00000164118
Uniprot IDs		Q6IPU0	Q9C0F1
PDB IDs		7PB8 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH	7PT5
Enriched GO Terms of Interacting Partners?		Centrosome Cycle
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