DHDDS

Description		dehydrodolichyl diphosphate synthase subunit
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Dehydrodolichyl Diphosphate Synthase Complex
	Molecular Function	Prenyltransferase Activity Protein Binding Transferase Activity Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups Ditrans,polycis-polyprenyl Diphosphate Synthase [(2E,6E)-farnesyl Diphosphate Specific] Activity Metal Ion Binding
	Biological Process	Protein Glycosylation Dolichyl Diphosphate Biosynthetic Process Lipid Metabolic Process Polyprenol Biosynthetic Process Dolichyl Monophosphate Biosynthetic Process
Pathways		Synthesis of dolichyl-phosphate Defective DHDDS causes RP59
Drugs
Diseases
GWAS		Caffeine consumption from tea ( 33287642) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560) Serum alkaline phosphatase levels ( 33339817)
Novel Interacting Genes		1 novel interacting genes: VRK2
Interacting Genes		3 interacting genes: LOX MT-ND1 NPC2
Entrez ID		79947
HPRD ID		12183
Ensembl ID		ENSG00000117682
Uniprot IDs		Q86SQ9
PDB IDs		6W2L 6Z1N 7PAX 7PAY 7PB0 7PB1
Enriched GO Terms of Interacting Partners?		Descending Aorta Development Ascending Aorta Development Organelle Envelope Peptidyl-lysine Oxidation Response To Xenobiotic Stimulus Platelet-derived Growth Factor Receptor-beta Signaling Pathway Protein-lysine 6-oxidase Activity Oxidoreductase Activity, Acting On The CH-NH2 Group Of Donors, Oxygen As Acceptor Protein Oxidation Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Mitochondrial Membrane Cholesterol Storage Glycolipid Transport Sterol Binding Regulation Of Isoprenoid Metabolic Process Regulation Of Bone Development Elastic Fiber Assembly NADH Dehydrogenase Activity Response To Oxidative Stress Regulation Of Interleukin-1-mediated Signaling Pathway Cellular Response To Chemokine
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