PI3 and KRT1

Number of citations of the paper that reports this interaction (PMID 8999895)
22

Data Source:
BioGRID (pull down)

		PI3	KRT1
Gene Name		peptidase inhibitor 3, skin-derived	keratin 1, type II
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Vesicular Exosome	Extracellular Space Nucleus Cytoskeleton Plasma Membrane Membrane Extracellular Matrix Keratin Filament Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity	Receptor Activity Structural Molecule Activity Protein Binding Carbohydrate Binding
	Biological Process	Copulation Negative Regulation Of Endopeptidase Activity	Complement Activation, Lectin Pathway Retina Homeostasis Response To Oxidative Stress Fibrinolysis Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Establishment Of Skin Barrier
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CELA1 CSTA EVPL KRT1 LOR	15 interactors: CALB2 CSTA DSP EVPL F12 FANCA FANCC IVL KNG1 KRT5 LOR MBL2 PI3 PRKCE YWHAQ
Entrez ID		5266	3848
HPRD ID		15947	00763
Ensembl ID		ENSG00000124102	ENSG00000167768
Uniprot IDs		P19957	P04264
PDB IDs		1FLE 2REL
Enriched GO Terms of Interacting Partners?		Skin Development Peptide Cross-linking Keratinocyte Differentiation Epidermal Cell Differentiation Epidermis Development Organ Development Keratinization Epithelial Cell Differentiation System Development Multicellular Organismal Development Anatomical Structure Development Developmental Process Protein Metabolic Process Epithelium Development Pancreas Morphogenesis Complement Activation, Lectin Pathway Exocrine Pancreas Development Tissue Development Establishment Of Skin Barrier Regulation Of Water Loss Via Skin Fibrinolysis	Peptide Cross-linking Keratinocyte Differentiation Epidermis Development Epidermal Cell Differentiation Skin Development Keratinization Epithelial Cell Differentiation Epithelium Development Blood Coagulation, Intrinsic Pathway Regulation Of Wound Healing Regulation Of Protein Processing Protein Activation Cascade Cytosolic Calcium Ion Homeostasis Tissue Development Positive Regulation Of Wound Healing Wound Healing Negative Regulation Of Endopeptidase Activity Negative Regulation Of Blood Coagulation Negative Regulation Of Peptidase Activity Negative Regulation Of Coagulation Positive Regulation Of Cellular Glucuronidation Response To Wounding Cellular Calcium Ion Homeostasis Negative Regulation Of Wound Healing Calcium Ion Homeostasis Positive Regulation Of Transport Anatomical Structure Development Acute Inflammatory Response Organ Development Negative Regulation Of Proteolysis Ventricular Compact Myocardium Morphogenesis Factor XII Activation TRAM-dependent Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Regulation Of Blood Coagulation Negative Regulation Of Hydrolase Activity Cellular Metal Ion Homeostasis Regulation Of Peptidase Activity Blood Coagulation Inflammatory Response Developmental Process Hemostasis Protein Metabolic Process Cellular Cation Homeostasis Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Localization To Adherens Junction Positive Regulation Of Fibrinolysis Cellular Ion Homeostasis Response To Stress
Tagcloud ?		antiapoptotic ark augmented ax1 axl cascades coincubation erk forebrain gas6 gn10 gnrh gt1 mek migrating olfactory pd98059 phosphoinositide postmigratory programmed protects rescued starved threonine tyro7 ufo windows withdrawal wortmannin	arose backcrosses bareskin bsk chr clustered corneal den denuded facility granulin grn hair intersubspecific junctional jup keratin kinds linkage mapped opacity plakoglobin portion rara recombination resembling rex rim3 spontaneously
Tagcloud (Difference) ?		antiapoptotic ark augmented ax1 axl cascades coincubation erk forebrain gas6 gn10 gnrh gt1 mek migrating olfactory pd98059 phosphoinositide postmigratory programmed protects rescued starved threonine tyro7 ufo windows withdrawal wortmannin	arose backcrosses bareskin bsk chr clustered corneal den denuded facility granulin grn hair intersubspecific junctional jup keratin kinds linkage mapped opacity plakoglobin portion rara recombination resembling rex rim3 spontaneously
Tagcloud (Intersection) ?