LNPEP and FATE1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LNPEP	FATE1
Gene Name		leucyl/cystinyl aminopeptidase	fetal and adult testis expressed 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Intracellular Lysosomal Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Early Endosome Lumen Perinuclear Region Of Cytoplasm	Endoplasmic Reticulum Integral Component Of Membrane
	Molecular Function	Aminopeptidase Activity Metallopeptidase Activity Zinc Ion Binding	Protein Binding
	Biological Process	Protein Polyubiquitination Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Proteolysis Cell-cell Signaling Female Pregnancy Protein Catabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I SMAD Protein Signal Transduction Membrane Organization
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Translocation of GLUT4 to the plasma membrane Endosomal/Vacuolar pathway Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation Adaptive Immune System
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		8 interactors: FATE1 FHOD1 REL SLC2A4 SMAD9 TCF4 TNKS TNKS2	49 interactors: AGTRAP AQP9 BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 CCDC155 CCDC70 CD302 CD79A CSF2RA DCTN5 EMD GPR25 INPP5K KCNS2 LNPEP MARCH2 MARCH5 MR1 NDUFB11 NRG4 NRSN1 PIN4 PRRG2 RNF183 RPRM SEC22A SEC22C SEC23B SLC38A1 SLC7A1 SNAP47 SYNDIG1 SYNE4 SYNGR1 SYNPR TBP TIMMDC1 TM4SF4 TMEM74 TRAF2 TRAF3IP3 USHBP1 USP20 YIPF4
Entrez ID		4012	89885
HPRD ID		01041	02346
Ensembl ID		ENSG00000113441	ENSG00000147378
Uniprot IDs		Q9UIQ6	Q969F0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Telomere Maintenance Via Telomerase Protein Auto-ADP-ribosylation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Protein ADP-ribosylation Regulation Of Canonical Wnt Signaling Pathway Protein Localization To Chromosome Regulation Of Transcription From RNA Polymerase II Promoter Wnt Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Wnt Signaling Pathway Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Carbohydrate Metabolic Process Positive Regulation Of DNA Replication Positive Regulation Of Organelle Organization Positive Regulation Of Signal Transduction Amylopectin Biosynthetic Process Protein Localization To Organelle Biosynthetic Process Multicellular Organism Growth Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of DNA Replication Fat Cell Differentiation Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Positive Regulation Of DNA Metabolic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Protein Poly-ADP-ribosylation Positive Regulation Of Wnt Signaling Pathway Protein Polyubiquitination Maintenance Of DNA Repeat Elements Regulation Of Cellular Component Organization Cellular Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Glucose Homeostasis Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Regulation Of Organelle Organization Embryonic Genitalia Morphogenesis Mullerian Duct Regression Myoblast Fate Commitment	Mitochondrial Protein Catabolic Process Membrane Organization Vesicle Fusion With Golgi Apparatus Vesicle Fusion Positive Regulation Of Mitochondrial Fission Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrial Fission Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Apoptotic Mitochondrial Changes Organelle Fusion Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Mitochondrion Organization ER To Golgi Vesicle-mediated Transport Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Transport Positive Regulation Of Release Of Cytochrome C From Mitochondria Membrane Fusion Establishment Of Localization In Cell Regulation Of Mitochondrial Membrane Permeability Chromosome Localization To Nuclear Envelope Involved In Synapsis Positive Regulation Of Renal Water Transport Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Cellular Localization Regulation Of Membrane Permeability Protein Autoubiquitination
Tagcloud ?		aminopeptidase compensated cystinyl disrupts evolutionarily feline footprint genetics hanging heterozygotes inc inked intron juvenile ko leucyl lexicon littermates lix1 mating mendelian muscular neuromuscular neuron recessive rodent rotarod sma transcript
Tagcloud (Difference) ?		aminopeptidase compensated cystinyl disrupts evolutionarily feline footprint genetics hanging heterozygotes inc inked intron juvenile ko leucyl lexicon littermates lix1 mating mendelian muscular neuromuscular neuron recessive rodent rotarod sma transcript
Tagcloud (Intersection) ?