LMO7 and EMD

Number of citations of the paper that reports this interaction (PMID 17620012)
31

Data Source:
BioGRID (affinity chromatography technology, pull down, affinity chromatography technology)

		LMO7	EMD
Gene Name		LIM domain 7	emerin
Image
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Cytoplasm Focal Adhesion	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Microtubule Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Zinc Ion Binding	Actin Binding Protein Binding Beta-tubulin Binding
	Biological Process	Protein Ubiquitination Regulation Of Signaling Regulation Of Cell Adhesion	Mitotic Cell Cycle Muscle Contraction Mitotic Nuclear Envelope Disassembly Mitotic Nuclear Envelope Reassembly Muscle Organ Development Negative Regulation Of Catenin Import Into Nucleus Skeletal Muscle Cell Differentiation Positive Regulation Of Protein Export From Nucleus Negative Regulation Of Fibroblast Proliferation Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Growth Factor Stimulus
Pathways			Mitotic Prophase Nuclear Envelope Breakdown Depolymerisation of the Nuclear Lamina Nuclear Envelope Reassembly Clearance of Nuclear Envelope Membranes from Chromatin Mitotic Anaphase Initiation of Nuclear Envelope Reformation Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS		Type 1 diabetes ( 21980299)
Protein-Protein Interactions		8 interactors: ABCA1 CALM1 EMD MDM2 PKM UBAC2 YWHAG YWHAQ	36 interactors: ABT1 ACTB ACTG2 AEN AKAP8L BANF1 BCLAF1 BEND7 BYSL CATSPER1 CCDC33 CEP70 COPS6 CREB3 CTNNBIP1 DPPA4 EFHC2 FATE1 GMCL1 LMNA LMO7 LPL LUZP4 MAB21L3 MAPK6 PAK7 PSME1 SH3GL2 SH3GL3 SYNE1 TRAF3IP3 TRIM42 VAV1 YTHDC1 ZNF165 ZNF232
Entrez ID		4008	2010
HPRD ID		05078	02309
Ensembl ID		ENSG00000136153	ENSG00000102119
Uniprot IDs		E9PLH4 J3KP06 Q8WWI1	P50402
PDB IDs		2EAQ	1JEI 2ODC 2ODG
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transport Regulation Of Intracellular Transport Positive Regulation Of Intracellular Transport Membrane Organization Regulation Of Cellular Localization Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cellular Localization Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of Protein Export From Nucleus Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Signal Transduction Substantia Nigra Development Regulation Of Protein Localization Regulation Of Signaling Cellular Response To Organic Substance Neural Nucleus Development Protein Localization Positive Regulation Of Mitochondrion Organization Positive Regulation Of CAMP Biosynthetic Process Programmed Cell Death Positive Regulation Of CAMP Metabolic Process Cell Death Death Positive Regulation Of Cyclic Nucleotide Metabolic Process Cellular Response To UV-C Cellular Response To Vitamin B1 Midbrain Development Regulation Of CAMP Biosynthetic Process Cellular Response To Light Stimulus Regulation Of Mitochondrion Organization Regulation Of CAMP Metabolic Process Positive Regulation Of Nucleocytoplasmic Transport Response To Organic Substance Cellular Protein Localization Cellular Response To Growth Factor Stimulus Response To Growth Factor Establishment Of Protein Localization Cellular Response To Radiation Glucose Metabolic Process Carbohydrate Catabolic Process Mitotic Cell Cycle Process Positive Regulation Of Intracellular Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Traversing Start Control Point Of Mitotic Cell Cycle Interleukin-1 Beta Secretion Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway	Mitotic Nuclear Envelope Reassembly Establishment Of Viral Latency Nuclear Envelope Reassembly Regulation Of DNA-templated Transcription, Initiation Nucleus Organization Apoptotic Process Mitotic Nuclear Envelope Disassembly Programmed Cell Death Cell Death Death Nuclear Envelope Disassembly Negative Regulation Of Signal Transduction Sterol Regulatory Element Binding Protein Import Into Nucleus Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Tagcloud ?		bcrp c9orf3 cassette cdyl chemotherapeutics chemotherapies conferred ctrl devised dock ehbp1 farnesol farnesylation farnesyltransferase foxa2 functionalized ine1 isoprenoid mdr1 mrp1 mrs2 neb numbl oils oncoproteins pharmacogenomic sesquiterpene stab2 urgently	adopt aforementioned arrangements arylacetamides azabicyclo bicycles bicyclo bicyclononanone bicyclononanones carbonyl diazabicycles diazabicyclononanones dipyridyl enantiomers geometries heterocyclic isoquinolines ketocyclazocine n7 nonan oxa pharmacophoric pm3 protonated protonation semiempirical stereoisomers substituents unravel
Tagcloud (Difference) ?		bcrp c9orf3 cassette cdyl chemotherapeutics chemotherapies conferred ctrl devised dock ehbp1 farnesol farnesylation farnesyltransferase foxa2 functionalized ine1 isoprenoid mdr1 mrp1 mrs2 neb numbl oils oncoproteins pharmacogenomic sesquiterpene stab2 urgently	adopt aforementioned arrangements arylacetamides azabicyclo bicycles bicyclo bicyclononanone bicyclononanones carbonyl diazabicycles diazabicyclononanones dipyridyl enantiomers geometries heterocyclic isoquinolines ketocyclazocine n7 nonan oxa pharmacophoric pm3 protonated protonation semiempirical stereoisomers substituents unravel
Tagcloud (Intersection) ?