LDHC and RBL2

Number of citations of the paper that reports this interaction (PMID 16600870)
9

Data Source:
BioGRID (two hybrid)

		LDHC	RBL2
Gene Name		lactate dehydrogenase C	retinoblastoma-like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Motile Cilium Extracellular Vesicular Exosome	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	L-lactate Dehydrogenase Activity	DNA Binding Protein Binding
	Biological Process	ATP Biosynthetic Process Lactate Biosynthetic Process From Pyruvate Lactate Oxidation Sperm Motility Cellular Carbohydrate Metabolic Process	Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Modification Regulation Of Lipid Kinase Activity Regulation Of Cell Cycle
Pathways			Cyclin D associated events in G1 G1 Phase G0 and Early G1 Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs		NADH
Diseases
GWAS		Amyloid A Levels ( 21124955)
Protein-Protein Interactions		2 interactors: BRCA1 RBL2	42 interactors: BRCA1 BRF1 BRF2 CCNA1 CCNA2 CCND1 CCND3 CCNE1 CDK2 CDK4 CDK6 CREG1 DCTN1 DGKZ E2F4 E2F5 EZH2 GRAMD4 HBP1 HDAC1 ID2 LBX1 LDHC MCM7 MNDA PCBD1 PHB PPP2CA RAF1 RBBP8 RBBP9 RINT1 SKP2 SMARCA4 SNW1 SUV39H1 SUV420H2 TAF1 TOP1 UBTF USP4 XBP1
Entrez ID		3948	5934
HPRD ID		01027	01576
Ensembl ID		ENSG00000166796	ENSG00000103479
Uniprot IDs		P07864	Q08999 Q8NE70
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K9 Acetylation Regulation Of Lipid Metabolic Process Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Centriole Replication Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Cell Cycle Regulation Of Histone H3-K4 Methylation Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Postreplication Repair Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of Fatty Acid Metabolic Process Regulation Of Gene Expression By Genetic Imprinting Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Genetic Imprinting Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Vascular Endothelial Growth Factor Production G2 DNA Damage Checkpoint Positive Regulation Of Histone Methylation Positive Regulation Of DNA Repair Cell Cycle Androgen Receptor Signaling Pathway Regulation Of Centrosome Duplication Protein Autoubiquitination Regulation Of Histone Acetylation Negative Regulation Of Lipid Biosynthetic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Vascular Endothelial Growth Factor Production	Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Regulation Of Cell Cycle Regulation Of Gene Expression Cell Cycle Process Regulation Of Metabolic Process Mitotic Cell Cycle Process Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cell Division Regulation Of Cell Proliferation Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cell Cycle RNA Metabolic Process Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cell Cycle Process Biosynthetic Process Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Mitotic Cell Cycle Chromatin Organization Positive Regulation Of Transcription, DNA-templated Regulation Of Cellular Process DNA-templated Transcription, Initiation Cellular Metabolic Process Organelle Organization Regulation Of Cellular Protein Metabolic Process Chromosome Organization Cellular Response To Stress Regulation Of Protein Kinase Activity
Tagcloud ?		aerobic artificial biogenesis blc connecting debate dense endurance exercise hcr heightened inborn lactate lcr max odf peroxisome pgc proliferator running spermatogenesis testes testis tr trained training twelve vital vo2	arginine bcl3 casp10 dap1 derepression epigenetic epigenetically governs hdac1 hodgkin hoxa5 hrk indirectly lymphoma master methyltransferase offer p52 polycomb prc2 prmt5 rb1 reactivation repression repressor retinoblastoma tp53k372 trigger turn
Tagcloud (Difference) ?		aerobic artificial biogenesis blc connecting debate dense endurance exercise hcr heightened inborn lactate lcr max odf peroxisome pgc proliferator running spermatogenesis testes testis tr trained training twelve vital vo2	arginine bcl3 casp10 dap1 derepression epigenetic epigenetically governs hdac1 hodgkin hoxa5 hrk indirectly lymphoma master methyltransferase offer p52 polycomb prc2 prmt5 rb1 reactivation repression repressor retinoblastoma tp53k372 trigger turn
Tagcloud (Intersection) ?