LDHC

Name	lactate dehydrogenase C
Structure
Novel Interactors	1 novel interactors: TIMM10B
Interactors	3 interactors: BRCA1 RBL2 SRPK2
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Cytosol Cilium Motile Cilium Extracellular Exosome Oxidoreductase Complex
	Molecular Function	Catalytic Activity L-lactate Dehydrogenase (NAD+) Activity Protein Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
	Biological Process	Lactate Metabolic Process ATP Biosynthetic Process Lactate Biosynthetic Process From Pyruvate Carboxylic Acid Metabolic Process Flagellated Sperm Motility Pyruvate Catabolic Process
Pathways	Pyruvate metabolism
Drugs	NADH
GWAS	Amyloid A serum levels ( 21124955 ) Amyotrophic lateral sclerosis (sporadic) ( 24529757 )
Entrez ID	3948
HPRD ID	01027
Ensembl ID	ENSG00000166796
Uniprot IDs	A0A140VKA7 P07864
PDB IDs	7EPM
GO Terms Enriched among Interactors ?	Negative Regulation Of Centriole Replication BRCA1-B Complex Histone H2AK127 Ubiquitin Ligase Activity Nuclear Ubiquitin Ligase Complex Cellular Response To Indole-3-methanol Negative Regulation Of Cell Cycle Process BRCA1-C Complex Negative Regulation Of Mitotic Cell Cycle Phase Transition Histone H2AK129 Ubiquitin Ligase Activity Negative Regulation Of Cell Cycle Phase Transition Response To Indole-3-methanol Negative Regulation Of Mitotic Cell Cycle Chromosome BRCA1-BARD1 Complex Regulation Of Cell Cycle Chromatin Organization Regulation Of Lipid Kinase Activity Nuclear Speck Organization TIM22 Mitochondrial Import Inner Membrane Insertion Complex Mitochondrial Intermembrane Space Chaperone Complex BRCA1-A Complex Ubiquitin-modified Histone Reader Activity R-loop Processing Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Centrosome Duplication XY Body Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Lateral Element Negative Regulation Of Cell Cycle Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway Gamma-tubulin Ring Complex DNA Strand Resection Involved In Replication Fork Processing DNA Repair Complex Random Inactivation Of X Chromosome Protein Transporter Activity Regulation Of Cell Cycle Phase Transition Nuclear Body Organization Protein Insertion Into Mitochondrial Inner Membrane RNA Polymerase Binding Negative Regulation Of Fatty Acid Biosynthetic Process Sex-chromosome Dosage Compensation Dosage Compensation By Inactivation Of X Chromosome Regulation Of Mitotic Cell Cycle Regulation Of DNA Damage Checkpoint