LAMP2 and AP4M1

Number of citations of the paper that reports this interaction (PMID 11139587)
23

Data Source:
HPRD (in vitro)

		LAMP2	AP4M1
Gene Name		lysosomal-associated membrane protein 2	adaptor-related protein complex 4, mu 1 subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Platelet Dense Granule Membrane Late Endosome Membrane Extracellular Vesicular Exosome	Golgi Trans Cisterna Trans-Golgi Network Coated Pit AP-type Membrane Coat Adaptor Complex Clathrin Adaptor Complex Extracellular Vesicular Exosome
	Molecular Function	Enzyme Binding Protein Domain Specific Binding	Transporter Activity
	Biological Process	Platelet Degranulation Blood Coagulation Platelet Activation Protein Stabilization	Intracellular Protein Transport Golgi To Endosome Transport Vesicle-mediated Transport
Pathways		Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: AP4M1 CTSA PIAS4 UCHL1	13 interactors: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22
Entrez ID		3920	9179
HPRD ID		02396	03803
Ensembl ID		ENSG00000005893	ENSG00000221838
Uniprot IDs		B7Z2R9 P13473	C9JC87 O00189
PDB IDs			3L81
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Keratinocyte Apoptotic Process Axon Target Recognition Axon Transport Of Mitochondrion Intracellular Transport Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage	Startle Response Synaptic Transmission, Glutamatergic Ionotropic Glutamate Receptor Signaling Pathway Glutamate Receptor Signaling Pathway Neuron-neuron Synaptic Transmission Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Membrane Depolarization Neuromuscular Process Regulation Of Synaptic Plasticity Regulation Of Receptor Internalization Calcium Ion Transmembrane Transport Synaptic Transmission Regulation Of Membrane Potential Regulation Of Synaptic Transmission Calcium Ion Transport Platelet Degranulation Transport Cell-cell Signaling Sensory Perception Of Pain Protein Localization Memory Directional Locomotion Regulation Of Signaling Learning Response To Ethanol Regulation Of Rubidium Ion Transport Ion Transmembrane Transport Regulation Of Endocytosis Platelet Activation Pigment Granule Maturation Endosome To Melanosome Transport Vesicle-mediated Transport Cellular Localization Response To Wounding Monoubiquitinated Protein Deubiquitination Positive Regulation Of Integrin-mediated Signaling Pathway Cellular Pigment Accumulation Regulation Of Vascular Endothelial Growth Factor Signaling Pathway Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Cerebellar Granule Cell Differentiation Negative Regulation Of Cell Cycle G2/M Phase Transition Golgi Vesicle Budding Metal Ion Transport Learning Or Memory Prepulse Inhibition Serotonin Metabolic Process Sleep
Tagcloud ?		albinism bloc colocalize confocal constituents disrupt disrupted encoded hair hypopigmentation localizations matp melanogenic melanosomal melanosomes misrouting oca oca2 oca4 oculocutaneous organelles pigmentation severely slc45a2 sorting subcellular trafficking transporters tyrosinase
Tagcloud (Difference) ?		albinism bloc colocalize confocal constituents disrupt disrupted encoded hair hypopigmentation localizations matp melanogenic melanosomal melanosomes misrouting oca oca2 oca4 oculocutaneous organelles pigmentation severely slc45a2 sorting subcellular trafficking transporters tyrosinase
Tagcloud (Intersection) ?