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INCA1 and THRSP
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
INCA1
THRSP
Description
inhibitor of CDK, cyclin A1 interacting protein 1
thyroid hormone responsive
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Molecular Function
Protein Kinase Inhibitor Activity
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Protein Binding
Cyclin Binding
Identical Protein Binding
Protein-containing Complex Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Molecular Function Inhibitor Activity
Biological Process
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Fibroblast Proliferation
Negative Regulation Of Fibroblast Proliferation
Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Lipid Metabolic Process
Response To Bacterium
Regulation Of Triglyceride Biosynthetic Process
Regulation Of Lipid Biosynthetic Process
Pathways
Carnitine shuttle
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS
Intraocular pressure (
29235454
)
Keratoconus (
33649486
)
Obesity-related traits (
23251661
)
Menarche (age at onset) (
25231870
)
Tourette syndrome (
30818990
)
Interacting Genes
236 interacting genes:
ABI2
ACTMAP
ACY3
AKAP8L
ANKRD28
ARMC7
ASPSCR1
ATG5
ATP6V0D2
ATPAF2
BAG3
BANF2
BOLA3
BPIFA1
C10orf55
C1orf35
C1orf50
C1orf56
C22orf39
CABP5
CCBE1
CCDC57
CCDC78
CCNA1
CDA
CDC23
CDK18
CDK2
CDK4
CDKN1A
CDKN2B
CDKN2D
CEP72
CHCHD2
CHCHD5
CHRD
CINP
CKS1B
CLIC3
CLK3
COL8A1
CPSF1
CSDC2
CSTF2
CTNNBIP1
CTTNBP2
CYSRT1
DAZAP2
DEF6
DMRT3
DMRTB1
DOK4
DPH7
DUSP13B
EFEMP2
EMD
EPHB6
EXOSC8
FAAP20
FAIM
FEM1A
FGF16
FHL2
FMR1
FRS3
GEM
GEMIN2
GRB2
GRXCR1
GSTO2
GTF2H5
GTPBP3
GYS1
HAUS1
HCK
HDAC4
HEMK1
HENMT1
HNRNPF
HOMER3
HOXA1
HR
HSD17B14
HYI
IL36RN
ILF2
KCTD7
KCTD9
KIAA1217
KIR2DL4
KLHL26
KLHL42
KRT33B
KRT5
KRT75
KRTAP15-1
KRTAP19-1
KRTAP19-5
KRTAP19-6
KRTAP5-6
KRTAP6-2
KRTAP6-3
KRTAP9-3
LENG8
LGALS3
LHX3
LMNTD2
LMO2
LMO3
LSM3
LYPLA2
MAD2L2
MAGED4B
MAGOHB
MALSU1
MARF1
MARK1
MATN3
MBLAC1
METAP1
MPP1
MSRB1
MTMR9
NATD1
NCK2
NDUFAF3
NEDD9
NEIL2
NEK6
NFKBID
NHSL2
NME7
NMRK1
NPAS2
NTAQ1
NUBP2
NUDT16L1
NUDT22
OR6B1
OSGIN1
PADI3
PATE1
PCSK5
PCYT2
PDP1
PEF1
PFDN5
PHF1
PLA2G10
PLSCR3
POLR1C
POLR3C
POP5
POU4F2
PRPH
PSMB2
PSMB8
PTGER3
R3HDM2
RAB5C
RALB
RAMAC
RBPMS
RECK
RFC3
RIPPLY3
RNF26
SAP18
SAXO4
SCNM1
SEC14L4
SHFL
SLC67A1-AS
SMG9
SMUG1
SNRPB
SPAG8
SPG21
SPOUT1
SPRY1
STAMBPL1
STK16
STT3B
SUOX
TBC1D7
TCL1A
TEAD4
TEKT4
TEX12
TFAP2A
TFAP2D
TFAP4
TFG
THAP6
THRSP
TIAL1
TPRX1
TRAPPC2
TRAPPC2B
TRAPPC6A
TRIB3
TRIM26
TRIM55
TRIM63
TRIM68
TRIP13
TRIP6
TSEN15
TSG101
TSSK3
TSTD2
TXNDC17
UBASH3B
UBE2D4
UBE2Z
UBTD2
UBXN2B
UFM1
UFSP1
VEZF1
VGLL3
VPS26C
VPS28
WWOX
YIPF3
YOD1
ZDHHC24
ZFAND3
ZMYND12
ZMYND19
ZNF205-AS1
ZNF32
ZNF446
ZNF747
ZNF765
ZNRD2
25 interacting genes:
AKT1
AURKA
BAG4
BCAR3
BRMS1
ERBB2
FGFR4
FZR1
HMMR
IGF1R
INCA1
KRAS
LSP1
PALB2
PARP1
PIK3CA
PTPN1
RB1CC1
SMAD4
STK11
TEPSIN
TGFB1
TSG101
WT1
ZMYND12
Entrez ID
388324
7069
HPRD ID
17150
03566
Ensembl ID
ENSG00000196388
ENSG00000151365
Uniprot IDs
Q0VD86
Q92748
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Binding
Intermediate Filament
Cytosol
COPII Vesicle Coating
Spindle Pole Centrosome
Cytoplasm
Nucleus
Identical Protein Binding
Cyclin A1-CDK2 Complex
MRNA Processing
Vesicle Coating
Positive Regulation Of Ubiquitin-dependent Endocytosis
Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Regulation Of Cell Population Proliferation
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Regulation Of Signal Transduction
Enzyme-linked Receptor Protein Signaling Pathway
Carbohydrate Homeostasis
Glucose Homeostasis
Negative Regulation Of Apoptotic Process
Regulation Of Intracellular Signal Transduction
Negative Regulation Of Programmed Cell Death
Regulation Of Protein Metabolic Process
Regulation Of Catalytic Activity
Regulation Of Cell Communication
Regulation Of Signaling
Insulin Receptor Signaling Pathway
Gland Development
Cellular Response To Growth Factor Stimulus
Apoptotic Process
Response To Growth Factor
Regulation Of Cellular Component Organization
Positive Regulation Of Cell Population Proliferation
Liver Development
Programmed Cell Death
Cell Death
Anoikis
Negative Regulation Of Cell Population Proliferation
Protein-containing Complex Binding
Protein Autophosphorylation
Cell Surface Receptor Signaling Pathway
Epithelial Cell Differentiation
Regulation Of Cell Growth
Positive Regulation Of Fibroblast Migration
Regulation Of Growth
Epidermal Growth Factor Receptor Signaling Pathway
Cellular Response To Glucose Stimulus
Regulation Of Protein Modification Process
Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway
Regulation Of MAPK Cascade
Positive Regulation Of MAPK Cascade
Regulation Of Protein Localization
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Cellular Response To Carbohydrate Stimulus
ERBB Signaling Pathway
Cellular Response To Peptide Hormone Stimulus
Positive Regulation Of Catalytic Activity
Cell Population Proliferation
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Tagcloud (Intersection)
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