INCA1 and CDKN2D

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		INCA1	CDKN2D
Gene Name		inhibitor of CDK, cyclin A1 interacting protein 1	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Cytoplasm Cytosol
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Cyclin Binding	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Protein Kinase Binding
	Biological Process	Negative Regulation Of Cell Proliferation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle DNA Synthesis Involved In DNA Repair Cell Cycle Arrest Sensory Perception Of Sound Negative Regulation Of Cell Proliferation Response To UV Negative Regulation Of Cell Growth Response To Retinoic Acid Response To Vitamin D Negative Regulation Of Phosphorylation Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Autophagic Cell Death Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways			Cyclin D associated events in G1 Oxidative Stress Induced Senescence G1 Phase Cellular Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		33 interactors: ARMC7 CABP5 CCNA1 CDC23 CDK2 CDKN2D CHCHD2 COL8A1 CTNNBIP1 DMRT3 EPHB6 FAM103A1 FHL2 FMR1 GRB2 HAUS1 NEK6 OSGIN1 PATE1 PTGER3 RBPMS SAP18 SCNM1 SEC14L4 SPG21 STAMBPL1 STK16 TRIP6 UBE2D4 UBXN2B VPS28 ZMYND19 ZNF205-AS1	11 interactors: APP BRCA1 C1orf94 CDK4 CDK6 HSD17B14 IKZF3 INCA1 NR4A1 NR4A2 TBC1D17
Entrez ID		388324	1032
HPRD ID		17150	02957
Ensembl ID		ENSG00000196388	ENSG00000129355
Uniprot IDs		Q0VD86	P55273
PDB IDs			1BD8 1BI8
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Division Mitotic Cell Cycle Process Regulation Of Mitotic Cell Cycle Phase Transition Cell Division Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Protein K11-linked Ubiquitination G1/S Transition Of Mitotic Cell Cycle Cell Cycle Process Regulation Of Metabolic Process Regulation Of Mitotic Cell Cycle Recruitment Of MRNA Capping Enzyme To RNA Polymerase II Holoenzyme Complex Regulation Of Cellular Protein Metabolic Process Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Ubiquitination Regulation Of Cell Cycle Process Cell Cycle Checkpoint Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Modification-dependent Protein Catabolic Process Nuclear Envelope Organization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Acute Inflammatory Response Atrial Cardiac Muscle Cell Development Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Cycle Regulation Of Cell Cycle Cellular Protein Catabolic Process Gene Expression Spindle Assembly RNA Processing Positive Regulation Of DNA-dependent DNA Replication Initiation Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Fever Generation	Intracellular Receptor Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Regulation Of Cell Death Regulation Of Cell Cycle Negative Regulation Of Cell Cycle Response To Steroid Hormone Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation Positive Regulation Of Cell Cycle Process Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cell Cycle Regulation Of Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Cycle Phase Transition Response To Lipid Response To Organic Cyclic Compound Negative Regulation Of Protein Metabolic Process Positive Regulation Of Fibroblast Proliferation Response To Hormone Positive Regulation Of Histone H4-K20 Methylation Cell Dedifferentiation Positive Regulation Of Histone H4-K16 Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription From RNA Polymerase II Promoter Death Regulation Of Cellular Protein Metabolic Process Forebrain Development Response To Abiotic Stimulus Regulation Of Fibroblast Proliferation Regulation Of Cell Cycle Arrest Steroid Hormone Mediated Signaling Pathway Habenula Development Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation General Adaptation Syndrome Regulation Of Cell Cycle Process Adult Locomotory Behavior Regulation Of Gene Expression Anatomical Structure Development Positive Regulation Of Mitotic Cell Cycle Regulation Of Protein Metabolic Process
Tagcloud ?		accompanied arrest bax bcl2 birc5 ccna1 cdk2 cdkn1a deregulation entering g2 lats2 microrna mir modification namely nasopharyngeal nine npc phenotypes possibly precursor preliminary progression suppressing tp53 transfected tw01 words	arrests cdk4 characterization cloning conserved enforced evolution evolutionary fibroblasts functionally g1 identity indeed inhibiting ink4 ink4d lnk4d maternally mouse neurulation p19ink4d regulator substitute transcripts traverse vertebrate xenopus xenopuslaevis xl
Tagcloud (Difference) ?		accompanied arrest bax bcl2 birc5 ccna1 cdk2 cdkn1a deregulation entering g2 lats2 microrna mir modification namely nasopharyngeal nine npc phenotypes possibly precursor preliminary progression suppressing tp53 transfected tw01 words	arrests cdk4 characterization cloning conserved enforced evolution evolutionary fibroblasts functionally g1 identity indeed inhibiting ink4 ink4d lnk4d maternally mouse neurulation p19ink4d regulator substitute transcripts traverse vertebrate xenopus xenopuslaevis xl
Tagcloud (Intersection) ?