INCA1 and CTNNBIP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		INCA1	CTNNBIP1
Gene Name		inhibitor of CDK, cyclin A1 interacting protein 1	catenin, beta interacting protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Beta-catenin Destruction Complex
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding Cyclin Binding	Protein Binding Beta-catenin Binding Armadillo Repeat Domain Binding
	Biological Process	Negative Regulation Of Cell Proliferation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway	Branching Involved In Ureteric Bud Morphogenesis Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Anterior/posterior Pattern Specification Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Binding Negative Regulation Of DNA Binding Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Monocyte Differentiation Positive Regulation Of Osteoblast Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Mesenchymal Cell Proliferation
Pathways			misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling TCF dependent signaling in response to WNT RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN Signaling by Wnt Signaling by WNT in cancer deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		33 interactors: ARMC7 CABP5 CCNA1 CDC23 CDK2 CDKN2D CHCHD2 COL8A1 CTNNBIP1 DMRT3 EPHB6 FAM103A1 FHL2 FMR1 GRB2 HAUS1 NEK6 OSGIN1 PATE1 PTGER3 RBPMS SAP18 SCNM1 SEC14L4 SPG21 STAMBPL1 STK16 TRIP6 UBE2D4 UBXN2B VPS28 ZMYND19 ZNF205-AS1	11 interactors: BEND5 CTNNA2 CTNNB1 EMD INCA1 JUP KRTAP10-3 KRTAP10-7 REL TCF7L2 USHBP1
Entrez ID		388324	56998
HPRD ID		17150	09677
Ensembl ID		ENSG00000196388	ENSG00000178585
Uniprot IDs		Q0VD86	Q9NSA3
PDB IDs			1LUJ 1M1E 1T08
Enriched GO Terms of Interacting Partners?		Mitotic Nuclear Division Mitotic Cell Cycle Process Regulation Of Mitotic Cell Cycle Phase Transition Cell Division Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Protein K11-linked Ubiquitination G1/S Transition Of Mitotic Cell Cycle Cell Cycle Process Regulation Of Metabolic Process Regulation Of Mitotic Cell Cycle Recruitment Of MRNA Capping Enzyme To RNA Polymerase II Holoenzyme Complex Regulation Of Cellular Protein Metabolic Process Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Protein Ubiquitination Regulation Of Cell Cycle Process Cell Cycle Checkpoint Regulation Of Vascular Permeability Involved In Acute Inflammatory Response Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Modification-dependent Protein Catabolic Process Nuclear Envelope Organization Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Acute Inflammatory Response Atrial Cardiac Muscle Cell Development Protein Targeting To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Cycle Regulation Of Cell Cycle Cellular Protein Catabolic Process Gene Expression Spindle Assembly RNA Processing Positive Regulation Of DNA-dependent DNA Replication Initiation Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Fever Generation	Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Regulation Of Canonical Wnt Signaling Pathway Cellular Response To Indole-3-methanol Regulation Of Wnt Signaling Pathway Positive Regulation Of Nucleocytoplasmic Transport Muscle Structure Development Positive Regulation Of Glycoprotein Biosynthetic Process Positive Regulation Of Protein Export From Nucleus Genitalia Morphogenesis Positive Regulation Of Signal Transduction Positive Regulation Of Glycoprotein Metabolic Process Positive Regulation Of Intracellular Protein Transport Regulation Of Cell Fate Specification Regulation Of Signal Transduction Regulation Of Cell Proliferation Regulation Of Nucleocytoplasmic Transport Skin Development Regulation Of Glycoprotein Biosynthetic Process Regulation Of Signaling Positive Regulation Of Intracellular Transport Regulation Of Protein Export From Nucleus Regulation Of Protein Localization Regulation Of Cell Fate Commitment Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Intracellular Protein Transport Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Epithelial Cell-cell Adhesion Regulation Of Oligodendrocyte Differentiation Myoblast Differentiation Adherens Junction Assembly Muscle Cell Differentiation Regulation Of Myelination Positive Regulation Of Protein Transport Positive Regulation Of Stem Cell Differentiation Genitalia Development Regulation Of Cellular Localization Regulation Of Epithelial To Mesenchymal Transition Digestive Tract Morphogenesis Regulation Of Glial Cell Differentiation Regulation Of Intracellular Transport Negative Regulation Of Cell Cycle Adherens Junction Organization Response To Organic Substance Canonical Wnt Signaling Pathway Positive Regulation Of Muscle Cell Differentiation Pancreas Development Single Organismal Cell-cell Adhesion Regulation Of Fibroblast Proliferation Regulation Of Gliogenesis
Tagcloud ?		accompanied arrest bax bcl2 birc5 ccna1 cdk2 cdkn1a deregulation entering g2 lats2 microrna mir modification namely nasopharyngeal nine npc phenotypes possibly precursor preliminary progression suppressing tp53 transfected tw01 words
Tagcloud (Difference) ?		accompanied arrest bax bcl2 birc5 ccna1 cdk2 cdkn1a deregulation entering g2 lats2 microrna mir modification namely nasopharyngeal nine npc phenotypes possibly precursor preliminary progression suppressing tp53 transfected tw01 words
Tagcloud (Intersection) ?