INSC and PARD3B

Number of citations of the paper that reports this interaction (PMID 16458856)
6

Data Source:
HPRD (in vivo)

		INSC	PARD3B
Gene Name		inscuteable homolog (Drosophila)	par-3 family cell polarity regulator beta
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Apical Part Of Cell	Tight Junction Endomembrane System Membrane
	Molecular Function
	Biological Process	Establishment Of Mitotic Spindle Orientation Nervous System Development Lung Epithelial Cell Differentiation	Cell Cycle Cell Division
Pathways
Drugs
Diseases
GWAS		Menarche (age at onset) ( 23667675) Obesity-related traits ( 23251661) Prostate cancer (gene x gene interaction) ( 22219177)	AIDS progression ( 21502085) Autism ( 22843504) Knee osteoarthritis ( 18471798)
Protein-Protein Interactions		5 interactors: GPSM1 GPSM2 LNX1 PARD3 PARD3B	8 interactors: INSC PARD6B SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 YWHAG
Entrez ID		387755	117583
HPRD ID		18803	09795
Ensembl ID		ENSG00000188487	ENSG00000116117
Uniprot IDs		A0PJX5 Q1MX18	E9PE87 Q8TEW8
PDB IDs		3SF4
Enriched GO Terms of Interacting Partners?		Establishment Of Cell Polarity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Establishment Or Maintenance Of Cell Polarity Apical Constriction Asymmetric Cell Division Cell Cycle	SMAD Protein Complex Assembly Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Transforming Growth Factor Beta Receptor Signaling Pathway Primary MiRNA Processing Kidney Epithelium Development Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Epithelial To Mesenchymal Transition Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Embryonic Pattern Specification Kidney Development Tube Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Renal System Development Production Of MiRNAs Involved In Gene Silencing By MiRNA Urogenital System Development Regulation Of Cell Development Mesoderm Development Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Cell Morphogenesis Gene Silencing By MiRNA Transcription Initiation From RNA Polymerase II Promoter Cellular Response To DsRNA Gastrulation Regulation Of Cellular Response To Growth Factor Stimulus Heart Development Epithelium Development Posttranscriptional Gene Silencing Positive Regulation Of Stem Cell Differentiation Cellular Response To Growth Factor Stimulus SMAD Protein Signal Transduction Response To Growth Factor DNA-templated Transcription, Initiation Tissue Morphogenesis System Development Gene Silencing By RNA Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To DsRNA Endoderm Development BMP Signaling Pathway Mesoderm Formation Regulation Of Cell Differentiation Regulation Of BMP Signaling Pathway Mesoderm Morphogenesis Cellular Protein Complex Assembly Multicellular Organismal Development
Tagcloud ?		allergy atopy betalactam clarified genotype genotyped genotypes hypersensitivity ige inflammation influence italian italy leucine link mirrored nod1 nod2 nothing polymorphisms predicted predictors repeat rich rs2066845 rs5743293 spain spanish tt	a2bp1 bcap29 carriage cog5 dentists dio2 dip dus4l dvwa esr1 finnish gdf5 hfe oa occupationally ptgs2 roa rs10953541 rs179945 rs1800470 rs3757713 rs716508 rs9340799 saw snpstats tbgf1 teachers tgfb1 trib1
Tagcloud (Difference) ?		allergy atopy betalactam clarified genotype genotyped genotypes hypersensitivity ige inflammation influence italian italy leucine link mirrored nod1 nod2 nothing polymorphisms predicted predictors repeat rich rs2066845 rs5743293 spain spanish tt	a2bp1 bcap29 carriage cog5 dentists dio2 dip dus4l dvwa esr1 finnish gdf5 hfe oa occupationally ptgs2 roa rs10953541 rs179945 rs1800470 rs3757713 rs716508 rs9340799 saw snpstats tbgf1 teachers tgfb1 trib1
Tagcloud (Intersection) ?