INSC and GPSM2

Number of citations of the paper that reports this interaction (PMID 16458856)
6

Data Source:
HPRD (in vivo)

		INSC	GPSM2
Gene Name		inscuteable homolog (Drosophila)	G-protein signaling modulator 2
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Apical Part Of Cell	Cytoplasm Cell Cortex Apical Part Of Cell
	Molecular Function		Protein Binding GTPase Regulator Activity Identical Protein Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Nervous System Development Lung Epithelial Cell Differentiation	Establishment Of Mitotic Spindle Orientation G-protein Coupled Receptor Signaling Pathway Regulation Of Catalytic Activity Lung Epithelial Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Menarche (age at onset) ( 23667675) Obesity-related traits ( 23251661) Prostate cancer (gene x gene interaction) ( 22219177)	Fat distribution (HIV) ( 21897333)
Protein-Protein Interactions		5 interactors: GPSM1 GPSM2 LNX1 PARD3 PARD3B	8 interactors: GLIS2 GNAI1 GNAI2 GNAI3 GNAO1 HRAS INSC NUMA1
Entrez ID		387755	29899
HPRD ID		18803	06609
Ensembl ID		ENSG00000188487	ENSG00000121957
Uniprot IDs		A0PJX5 Q1MX18	P81274
PDB IDs		3SF4	3SF4
Enriched GO Terms of Interacting Partners?		Establishment Of Cell Polarity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Establishment Or Maintenance Of Cell Polarity Apical Constriction Asymmetric Cell Division Cell Cycle	Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Cell Cycle Blood Coagulation Cell Division Hemostasis Negative Regulation Of Adenylate Cyclase Activity Regulation Of Body Fluid Levels Synaptic Transmission Negative Regulation Of Lyase Activity Wound Healing Platelet Activation Establishment Of Mitotic Spindle Orientation Negative Regulation Of CAMP Biosynthetic Process Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Negative Regulation Of CAMP Metabolic Process Response To Wounding Lung Development Respiratory Tube Development Negative Regulation Of Nucleotide Metabolic Process Respiratory System Development Spindle Localization Lung Epithelial Cell Differentiation Lung Cell Differentiation Vesicle Fusion Cell-cell Signaling Regulation Of Adenylate Cyclase Activity Lung Epithelium Development Activation Of MAPKK Activity Regulation Of Cyclase Activity Organelle Fusion G-protein Coupled Receptor Signaling Pathway Regulation Of CAMP Biosynthetic Process Establishment Of Cell Polarity Regulation Of CAMP Metabolic Process Membrane Fusion Mitotic Cell Cycle Process Cell Activation Tube Development Establishment Or Maintenance Of Cell Polarity Mitotic Cell Cycle Cell Surface Receptor Signaling Pathway Organelle Organization Positive Regulation Of Rac Protein Signal Transduction Regulation Of Calcium Ion Transport Negative Regulation Of Catalytic Activity Positive Regulation Of MiRNA Metabolic Process Response To Organonitrogen Compound
Tagcloud ?		allergy atopy betalactam clarified genotype genotyped genotypes hypersensitivity ige inflammation influence italian italy leucine link mirrored nod1 nod2 nothing polymorphisms predicted predictors repeat rich rs2066845 rs5743293 spain spanish tt	camk1 centriole dkk1 enah endosome geo inference kcnq3 kpna2 lcn2 lef1 lysosome map2k6 multivesicular nkx2 nr5a1 nup62 ontology phosphoinositide sfrp4 slc4a3 sort1 sstr5 stx1a subnetwork tbl3 transport tshb ube2c
Tagcloud (Difference) ?		allergy atopy betalactam clarified genotype genotyped genotypes hypersensitivity ige inflammation influence italian italy leucine link mirrored nod1 nod2 nothing polymorphisms predicted predictors repeat rich rs2066845 rs5743293 spain spanish tt	camk1 centriole dkk1 enah endosome geo inference kcnq3 kpna2 lcn2 lef1 lysosome map2k6 multivesicular nkx2 nr5a1 nup62 ontology phosphoinositide sfrp4 slc4a3 sort1 sstr5 stx1a subnetwork tbl3 transport tshb ube2c
Tagcloud (Intersection) ?