PARD3B and PARD6B

Number of citations of the paper that reports this interaction (PMID 12234671)
18

Data Source:
HPRD (in vitro)

		PARD3B	PARD6B
Gene Name		par-3 family cell polarity regulator beta	par-6 family cell polarity regulator beta
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Tight Junction Endomembrane System Membrane	Nucleus Cytoplasm Cytosol Plasma Membrane Tight Junction Cell Cortex Protein Complex Apical Part Of Cell Extracellular Vesicular Exosome
	Molecular Function		Protein Binding
	Biological Process	Cell Cycle Cell Division	Protein Complex Assembly Cell-cell Junction Assembly Cell Cycle Establishment Or Maintenance Of Cell Polarity Axonogenesis Regulation Of Cell Migration Cell Junction Assembly Cell-cell Junction Organization Cell Division Tight Junction Assembly
Pathways			Cell junction organization Cell-cell junction organization Tight junction interactions
Drugs
Diseases
GWAS		AIDS progression ( 21502085) Autism ( 22843504) Knee osteoarthritis ( 18471798)	Bipolar disorder ( 21771265)
Protein-Protein Interactions		8 interactors: INSC PARD6B SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 YWHAG	22 interactors: APP CDC42 CEP76 GMCL1 GOLGA2 HTRA1 MPP5 PARD3 PARD3B PARD6A PNMA1 PRKCG PRKCI PRKCZ RAC1 RHOJ RHOQ TCP10 WDR83 YWHAB YWHAH YWHAZ
Entrez ID		117583	84612
HPRD ID		09795	18703
Ensembl ID		ENSG00000116117	ENSG00000124171
Uniprot IDs		E9PE87 Q8TEW8	Q9BYG5
PDB IDs
Enriched GO Terms of Interacting Partners?		SMAD Protein Complex Assembly Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Mesonephros Development Transforming Growth Factor Beta Receptor Signaling Pathway Primary MiRNA Processing Kidney Epithelium Development Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Epithelial To Mesenchymal Transition Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Embryonic Pattern Specification Kidney Development Tube Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Renal System Development Production Of MiRNAs Involved In Gene Silencing By MiRNA Urogenital System Development Regulation Of Cell Development Mesoderm Development Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Cell Morphogenesis Involved In Differentiation Regulation Of Cell Morphogenesis Gene Silencing By MiRNA Transcription Initiation From RNA Polymerase II Promoter Cellular Response To DsRNA Gastrulation Regulation Of Cellular Response To Growth Factor Stimulus Heart Development Epithelium Development Posttranscriptional Gene Silencing Positive Regulation Of Stem Cell Differentiation Cellular Response To Growth Factor Stimulus SMAD Protein Signal Transduction Response To Growth Factor DNA-templated Transcription, Initiation Tissue Morphogenesis System Development Gene Silencing By RNA Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Response To DsRNA Endoderm Development BMP Signaling Pathway Mesoderm Formation Regulation Of Cell Differentiation Regulation Of BMP Signaling Pathway Mesoderm Morphogenesis Cellular Protein Complex Assembly Multicellular Organismal Development	Cell-cell Junction Organization Enzyme Linked Receptor Protein Signaling Pathway Tight Junction Assembly Regulation Of Cellular Component Organization Membrane Organization Cellular Response To Growth Factor Stimulus Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Apical Junction Assembly Wound Healing Response To Growth Factor Platelet Activation Positive Regulation Of Cell Death Actin Filament-based Process Cellular Protein Localization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Establishment Of Protein Localization Intracellular Signal Transduction Blood Coagulation Regulation Of Cellular Localization Hemostasis Response To Wounding Cellular Component Assembly Regulation Of Apoptotic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Transport Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Protein Localization Cell-cell Junction Assembly Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Glucose Import Neurogenesis Positive Regulation Of Glucose Transport Regulation Of Body Fluid Levels Nervous System Development Regulation Of Organelle Organization Actin Cytoskeleton Organization Defense Response Establishment Of Golgi Localization Neuron Development Protein Localization To Membrane Cellular Localization Neuron Projection Morphogenesis Anatomical Structure Morphogenesis Establishment Or Maintenance Of Cell Polarity Protein Localization Regulation Of Glucose Import Positive Regulation Of Mitochondrion Organization
Tagcloud ?		a2bp1 bcap29 carriage cog5 dentists dio2 dip dus4l dvwa esr1 finnish gdf5 hfe oa occupationally ptgs2 roa rs10953541 rs179945 rs1800470 rs3757713 rs716508 rs9340799 saw snpstats tbgf1 teachers tgfb1 trib1	adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify vps4b wizened
Tagcloud (Difference) ?		a2bp1 bcap29 carriage cog5 dentists dio2 dip dus4l dvwa esr1 finnish gdf5 hfe oa occupationally ptgs2 roa rs10953541 rs179945 rs1800470 rs3757713 rs716508 rs9340799 saw snpstats tbgf1 teachers trib1	adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pgp pkcalpha rh123 sgh snap47 vamp3 vamp4 verify vps4b wizened
Tagcloud (Intersection) ?		tgfb1