INSC

Description		INSC spindle orientation adaptor protein
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Cell Cortex Protein-containing Complex Apical Cortex
	Molecular Function	Protein Binding Cytoskeletal Anchor Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity
	Biological Process	Nervous System Development Asymmetric Cell Division Regulation Of Asymmetric Cell Division Cell Differentiation Regulation Of Protein Stability Apical Protein Localization
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Drugs
Diseases
GWAS		Expressive vocabulary in infants ( 25226531) Heel bone mineral density ( 28869591 30598549) Menarche (age at onset) ( 23667675) Obesity-related traits ( 23251661)
Interacting Genes		17 interacting genes: CCDC187 GEM GPANK1 GPSM1 GPSM2 LHX3 LNX1 PARD3 PARD3B PRR35 RUSC1 SMARCD1 SORBS3 TEKT3 TTC23 USP54 ZNF587
Entrez ID		387755
HPRD ID		18803
Ensembl ID		ENSG00000188487
Uniprot IDs		Q1MX18
PDB IDs		3SF4
Enriched GO Terms of Interacting Partners?		Centrosome Localization Cell Cortex Establishment Of Centrosome Localization Organelle Localization Microtubule Cytoskeleton Organization Microtubule-based Process GDP-dissociation Inhibitor Activity Establishment Of Organelle Localization Cytoskeleton Organization GTPase Regulator Activity G-protein Alpha-subunit Binding Apical Junction Complex Establishment Of Mitotic Spindle Orientation Establishment Of Mitotic Spindle Localization Establishment Of Spindle Orientation Regulation Of Brood Size Outer Acrosomal Membrane Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Establishment Of Spindle Localization Organelle Organization Spindle Localization Medial Motor Column Neuron Differentiation Prolactin Secreting Cell Differentiation Lateral Cell Cortex
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