KRT7 and ATF7IP

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		KRT7	ATF7IP
Gene Name		keratin 7, type II	activating transcription factor 7 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Intermediate Filament Keratin Filament Extracellular Vesicular Exosome	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	Structural Molecule Activity Protein Binding	Transcription Corepressor Activity Protein Binding ATPase Activity
	Biological Process	Viral Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Transcription, DNA-templated Viral Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Pathways			Chromatin modifying enzymes Chromatin organization PKMTs methylate histone lysines
Drugs
Diseases
GWAS			Prostate-specific antigen levels ( 23359319) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 23666240)
Protein-Protein Interactions		8 interactors: ATF7IP EGFR HSPA1A KDM1A KRT13 KRT17 KRT27 LAPTM5	68 interactors: A2M ACTB ACTG1 AP1B1 CADM1 CEP250 COL4A2 CREB1 CSPG4 DISC1 DMTF1 DNM2 EPG5 FLNB FLT4 GMEB1 GTF2E2 GTF2F1 GTF2H1 HEYL HLA-B HSPG2 KIF13A KRT7 LAMA4 LAMA5 LAMC1 LUC7L2 MACF1 MBD1 MCAM MED4 MRI1 NOMO1 NPR1 PAPPA PAPPA2 PCDH1 PEX6 PIAS3 PKD1 PLEKHB2 POLR2C POLR2D POLR2G PRSS8 PSG3 QRICH1 RPS3A RRBP1 SENP3 SETDB1 SLC12A4 SMAD4 SP1 SPTBN1 SREBF2 STBD1 STRN SUMO3 SUSD1 SVEP1 TRIP12 TTC3 UBE2I ZBTB6 ZNF350 ZNF518A
Entrez ID		3855	55729
HPRD ID		01014	09811
Ensembl ID		ENSG00000135480	ENSG00000171681
Uniprot IDs		P08729	B3KNI7 B3KQF8 F5GX74 G3V1U0 Q6VMQ6
PDB IDs			2RPQ
Enriched GO Terms of Interacting Partners?		Hair Follicle Development Hair Cycle Process Hair Cycle Positive Regulation Of Erythrocyte Differentiation Skin Development Hair Follicle Morphogenesis Tongue Development Regulation Of Erythrocyte Differentiation Epidermis Development Epidermis Morphogenesis Skin Morphogenesis Organ Morphogenesis Positive Regulation Of Myeloid Cell Differentiation Alkanesulfonate Metabolic Process Regulation Of Primitive Erythrocyte Differentiation Morphogenesis Of An Epithelium Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Cellular Heat Acclimation Astrocyte Activation Regulation Of Response To DNA Damage Stimulus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Tissue Morphogenesis Positive Regulation Of Cellular Biosynthetic Process Organ Development Activation Of Phospholipase A2 Activity Cellular Response To Acid Chemical Regulation Of Myeloid Cell Differentiation Positive Regulation Of Phospholipase A2 Activity Response To Cobalamin Response To UV-A Response To Hydroxyisoflavone Regulation Of Cellular Component Organization Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Positive Regulation Of Superoxide Anion Generation Histone H3-K4 Demethylation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Hair Follicle Development Negative Regulation Of Cell Death Positive Regulation Of Megakaryocyte Differentiation Negative Regulation Of Inclusion Body Assembly Positive Regulation Of Catenin Import Into Nucleus Regulation Of Protein Metabolic Process	Transcription Initiation From RNA Polymerase II Promoter Viral Process Positive Regulation Of Viral Transcription Cell Differentiation DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Regulation Of Viral Transcription 7-methylguanosine RNA Capping Positive Regulation Of Viral Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation RNA Biosynthetic Process Developmental Process Transcription, DNA-templated Anatomical Structure Development Regulation Of Viral Process Post-Golgi Vesicle-mediated Transport Macromolecule Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Gene Expression RNA Metabolic Process Extracellular Matrix Disassembly Cellular Macromolecule Biosynthetic Process Anatomical Structure Morphogenesis System Development Cell Junction Assembly Cardiovascular System Development Stem Cell Differentiation Anatomical Structure Formation Involved In Morphogenesis Biosynthetic Process Nervous System Development Neurogenesis Angiogenesis Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Golgi To Plasma Membrane Protein Transport Somatic Stem Cell Maintenance Protein Sumoylation Positive Regulation Of Gene Expression Multicellular Organismal Development Generation Of Neurons Stem Cell Development Blood Vessel Development Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Axon Guidance Golgi Vesicle Transport Vasculature Development
Tagcloud ?		aldh1 ciliated columnar exposes foxj1 gynaecological hgsc hgscs krt5 layered lef1 mem membraneous nests outgrowths oviduct oviductal oviducts pax2 pseudostratified rcn1 scout scouts stathmin stins tubal walthard wcn wcns	acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Difference) ?		aldh1 ciliated columnar exposes foxj1 gynaecological hgsc hgscs krt5 layered lef1 mem membraneous nests outgrowths oviduct oviductal oviducts pax2 pseudostratified rcn1 scout scouts stathmin stins tubal walthard wcn wcns	acgh adherent cce cd15 cd29 cd44 cd90 continuously csmd1 cultivation cytokeratins cytometric devastating doubling explant grin2b hypercalcemia hypercalcemic karyotype lentiviral oligo outgrowth paralleled park2 proliferating sccoht similarities subpopulations vimentin
Tagcloud (Intersection) ?