KRT7 and KRT13

Number of citations of the paper that reports this interaction (PubMedID 11591653)
29

Data Source:
HPRD (in vivo)

		KRT7	KRT13
Description		keratin 7	keratin 13
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome	Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Structural Molecule Activity Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Keratinization Intermediate Filament Organization	Morphogenesis Of An Epithelium Cytoskeleton Organization Epithelial Cell Differentiation Regulation Of Translation In Response To Stress Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope Developmental Lineage of Pancreatic Ductal Cells	Keratinization Formation of the cornified envelope
Drugs		Primaquine Verpasep caltespen
Diseases			White sponge nevus
GWAS		Blond vs. brown/black hair color ( 30531825) Diisocyanate-induced asthma ( 25918132)
Interacting Genes		11 interacting genes: ATF7IP EGFR HMGB1 HSPA1A KDM1A KRT13 KRT17 KRT27 LAPTM5 LINC01554 UBE3A	70 interacting genes: ABI2 ABI3 AIRIM AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf216 CATSPERT CCHCR1 CCNC CEP57 CEP57L1 CFTR DES DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GLYCTK GOLGA8EP GRAP2 HGS HOOK3 IFT20 KLC3 KLC4 KRT1 KRT2 KRT20 KRT3 KRT5 KRT6A KRT6B KRT6C KRT7 KRT71 KRT72 KRT74 KRT75 KRT76 KRT78 KRT79 KRT8 KRT81 KRT85 LSM2 MOS MYH1 MYO15B NEFL NEIL3 PPP1R18 PSMA1 PSMB1 PSMB2 RTL8B SGF29 SPG21 TLE5 TMSB4X TRIM42 TSG101 TXLNA TXLNB ZNF688
Entrez ID		3855	3860
HPRD ID		01014	01016
Ensembl ID		ENSG00000135480	ENSG00000171401
Uniprot IDs		P08729	A1A4E9 P13646
PDB IDs		4XIF
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Morphogenesis Of An Epithelium Tissue Morphogenesis Regulation Of Protein Ubiquitination Positive Regulation Of Protein Metabolic Process Transcription Corepressor Activity Keratinization Hair Cycle Process Regulation Of Post-translational Protein Modification Supramolecular Fiber Organization Regulation Of Protein Metabolic Process Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Protein Ubiquitination Regulation Of Protein Modification Process Positive Regulation Of Post-translational Protein Modification Positive Regulation Of Protein Modification Process Positive Regulation Of Macromolecule Biosynthetic Process Enzyme Binding Positive Regulation Of Biosynthetic Process Hair Follicle Morphogenesis Regulation Of Ubiquitin-dependent Protein Catabolic Process Structural Molecule Activity Regulation Of Activated T Cell Proliferation Negative Regulation Of Type II Interferon Production Positive Regulation Of Interleukin-12 Production Positive Regulation Of Macromolecule Metabolic Process Regulation Of Cellular Response To Stress Regulation Of Cell Population Proliferation Cell Differentiation Regulation Of DNA Repair Multivesicular Body, Internal Vesicle Lumen Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Response To Steroid Hormone Positive Regulation Of Myeloid Progenitor Cell Differentiation Intermediate Filament Polymerization Cytoskeleton Organization Intermediate Filament Cytoskeleton Sperm Entry Positive Regulation Of Golgi Lumen Acidification Induction Of Programmed Cell Death Negative Regulation Of Pre-B Cell Receptor Expression Positive Regulation Of Lysosomal Membrane Permeability Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction	Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Keratin Filament Intermediate Filament Keratinization Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Intermediate Filament Cytoskeleton Cytosol Structural Constituent Of Cytoskeleton Intermediate Filament Polymerization Or Depolymerization Extracellular Exosome Cytoskeleton Cytoplasm Protein Binding Proteasome Core Complex Epidermis Development Actin-based Cell Projection
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