RPL7 and ZNF7

Number of citations of the paper that reports this interaction (PubMedID 9268371)
0

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		RPL7	ZNF7
Description		ribosomal protein L7	zinc finger protein 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Endoplasmic Reticulum Cytosol Ribosome Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Cytosolic Ribosome Ribonucleoprotein Complex	Nucleus
	Molecular Function	DNA Binding RNA Binding MRNA Binding Structural Constituent Of Ribosome Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Cytoplasmic Translation RRNA Processing Translation Ribosomal Large Subunit Biogenesis	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide Ribosome Quality Control (RQC) complex extracts and degrades nascent peptide PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Drugs
Diseases
GWAS		Anthracycline-induced cardiotoxicity in early breast cancer ( 32378780) Crohn's disease ( 22412388) Fasting glucose ( 33381925)	Logical memory (immediate recall) in normal cognition ( 29274321)
Interacting Genes		14 interacting genes: DARS1-AS1 DUX4 IL7R IPO5 NR4A1 OGT PHC2 PPP1CC PTEN RAN SGO1 UBE2I YWHAQ ZNF7	4 interacting genes: MAPK3 RBM11 RPL7 TADA3
Entrez ID		6129	7553
HPRD ID		05004	01918
Ensembl ID		ENSG00000147604	ENSG00000147789
Uniprot IDs		A8MUD9 P18124	B4DWJ4 E9PIH3 E9PJX9 F5H290 P17097
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6IP5 6IP6 6IP8 6LQM 6LSR 6LSS 6LU8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6W6L 6XA1 6Y0G 6Y2L 6Y57 6Y6X 6Z6L 6Z6M 6Z6N 6ZM7 6ZME 6ZMI 6ZMO 7BHP 7F5S 7OW7 7QVP 7XNX 7XNY 8A3D 8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL0 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8G5Y 8G5Z 8G60 8G61 8G6J 8GLP 8IDT 8IDY 8IE3 8IFD 8IFE 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8JDJ 8JDK 8JDL 8JDM 8K2C 8OHD 8OJ0 8OJ5 8OJ8 8QFD 8QOI 8QYX 8RL2 8UKB 8XSX 8XSY 8XSZ 8Y0W 8Y0X 8YOO 8YOP 9C3H 9G8M 9GMO
Enriched GO Terms of Interacting Partners?		Nucleoplasm Chromosome Segregation Non-canonical Inflammasome Complex Assembly Nuclear Chromosome Segregation Nuclear Transport Nucleocytoplasmic Transport Nuclear Pore Nucleus Protein Import Into Nucleus Cytosol Regulation Of Nucleocytoplasmic Transport Import Into Nucleus Negative Regulation Of Cell Cycle Circadian Rhythm Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Localization To Nucleus Positive Regulation Of Protein Import Into Nucleus Mitotic Sister Chromatid Segregation Cell Division Sister Chromatid Segregation Regulation Of RNA Metabolic Process Regulation Of Cellular Localization Protein Domain Specific Binding Negative Regulation Of Synaptic Vesicle Clustering SUMO Conjugating Enzyme Activity Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Macromolecule Metabolic Process Membrane Assembly Regulation Of Protein Import Into Nucleus Positive Regulation Of Nucleocytoplasmic Transport Rhythmic Process Nuclear Membrane Interleukin-7 Receptor Activity Regulation Of Intracellular Transport Circadian Regulation Of Gene Expression Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Protein Localization To Organelle Phosphatase Activity Regulation Of Cell Size
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