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KLRD1 and KLRC2
Number of citations of the paper that reports this interaction (PMID
10320637
)
1
Data Source:
HPRD
(in vivo)
KLRD1
KLRC2
Gene Name
killer cell lectin-like receptor subfamily D, member 1
killer cell lectin-like receptor subfamily C, member 2
Image
Gene Ontology Annotations
Cellular Component
Plasma Membrane
External Side Of Plasma Membrane
Integral Component Of Membrane
Receptor Complex
Plasma Membrane
Integral Component Of Plasma Membrane
Receptor Complex
Molecular Function
Transmembrane Signaling Receptor Activity
Protein Binding
MHC Class I Protein Complex Binding
Carbohydrate Binding
Protein Antigen Binding
Transmembrane Signaling Receptor Activity
Protein Binding
MHC Class I Protein Complex Binding
Carbohydrate Binding
Protein Antigen Binding
Biological Process
Natural Killer Cell Mediated Immunity
Cell Surface Receptor Signaling Pathway
Innate Immune Response
Regulation Of Immune Response
Natural Killer Cell Mediated Immunity
Cellular Defense Response
Signal Transduction
Innate Immune Response
Pathways
DAP12 signaling
DAP12 interactions
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Adaptive Immune System
Innate Immune System
DAP12 signaling
DAP12 interactions
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
6 interactors:
HLA-B
HLA-E
HLA-G
KLRC1
KLRC2
KLRC3
3 interactors:
FBP1
HLA-E
KLRD1
Entrez ID
3824
3822
HPRD ID
04204
04202
Ensembl ID
ENSG00000134539
ENSG00000205809
Uniprot IDs
F6WZH4
Q13241
Q53ZY6
P26717
PDB IDs
1B6E
3BDW
3CDG
3CII
2L35
Enriched GO Terms of Interacting Partners
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Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent
Protection From Natural Killer Cell Mediated Cytotoxicity
Cellular Defense Response
Positive Regulation Of T Cell Mediated Cytotoxicity
Regulation Of T Cell Mediated Cytotoxicity
Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity
Positive Regulation Of Leukocyte Mediated Cytotoxicity
Positive Regulation Of T Cell Mediated Immunity
Positive Regulation Of Cell Killing
Regulation Of Leukocyte Mediated Cytotoxicity
Type I Interferon Signaling Pathway
Cellular Response To Type I Interferon
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Response To Type I Interferon
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Interferon-gamma-mediated Signaling Pathway
Regulation Of Dendritic Cell Differentiation
Positive Regulation Of Adaptive Immune Response
Cellular Response To Interferon-gamma
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
Defense Response
Response To Interferon-gamma
Antigen Processing And Presentation Of Endogenous Antigen
Regulation Of Adaptive Immune Response
Antigen Processing And Presentation Of Peptide Antigen
Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Natural Killer Cell Mediated Immunity
Innate Immune Response
Regulation Of Immune Response
Antigen Processing And Presentation
Negative Regulation Of Innate Immune Response
Negative Regulation Of Immune System Process
Cytokine-mediated Signaling Pathway
Immune Response
Regulation Of Interleukin-12 Production
Regulation Of Immune System Process
Signal Transduction
Signaling
Cell Communication
Cellular Response To Cytokine Stimulus
Positive Regulation Of Immune Response
Response To Stress
Negative Regulation Of Immune Response
Response To Cytokine
Cellular Response To Stimulus
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent
Immune System Process
Positive Regulation Of Immune System Process
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib
Positive Regulation Of Regulatory T Cell Differentiation
Protection From Natural Killer Cell Mediated Cytotoxicity
Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib
Cellular Response To Magnesium Ion
Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity
Negative Regulation Of Glycolytic Process
Antigen Processing And Presentation Of Endogenous Antigen
Fructose Metabolic Process
Response To Magnesium Ion
Positive Regulation Of Natural Killer Cell Mediated Immunity
Fructose 6-phosphate Metabolic Process
Regulation Of Natural Killer Cell Mediated Cytotoxicity
Regulation Of Natural Killer Cell Mediated Immunity
Natural Killer Cell Mediated Immunity
Regulation Of Glycolytic Process
Innate Immune Response
Regulation Of Immune Response
Negative Regulation Of Innate Immune Response
Regulation Of Gluconeogenesis
Gluconeogenesis
Cellular Response To Drug
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Small GTPase Mediated Signal Transduction
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent
Hexose Biosynthetic Process
Immune Response
Protein Homotetramerization
Regulation Of Immune System Process
Defense Response
Regulation Of Generation Of Precursor Metabolites And Energy
Positive Regulation Of T Cell Mediated Cytotoxicity
Regulation Of T Cell Mediated Cytotoxicity
Positive Regulation Of Leukocyte Mediated Cytotoxicity
Protein Tetramerization
Positive Regulation Of T Cell Mediated Immunity
Positive Regulation Of Cell Killing
Regulation Of Glucose Metabolic Process
Regulation Of Leukocyte Mediated Cytotoxicity
Type I Interferon Signaling Pathway
Cellular Response To Type I Interferon
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Response To Type I Interferon
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Interferon-gamma-mediated Signaling Pathway
Cellular Response To Metal Ion
Negative Regulation Of Immune Response
Cellular Response To Inorganic Substance
Glucose Metabolic Process
Cellular Response To Interferon-gamma
Positive Regulation Of Adaptive Immune Response
Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I
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