| Name |
potassium inwardly rectifying channel subfamily J member 2 |
potassium inwardly rectifying channel subfamily J member 16 |
| Structure |
|
No pdb structure
|
| GO Annotations |
Cellular Component |
|
|
| Molecular Function |
|
|
| Biological Process |
|
|
| Pathways |
|
|
| Drugs |
|
None
|
| Diseases |
|
None
|
| GWAS |
- Adolescent idiopathic scoliosis (severe) ( 24023777
)
- Alanine aminotransferase levels ( 33547301
)
- Appendicular lean mass ( 33097823
)
- Aspartate aminotransferase levels ( 33547301
)
- Atrial fibrillation ( 29892015
)
- Birth weight ( 31043758
)
- Chin dimples ( 27182965
)
- Dentures ( 31235808
)
- Depressive episodes in bipolar disorder ( 26297903
)
- Early cardiac repolarization ( 22342860
)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098
)
- Electrocardiographic traits (multivariate) ( 32602732
)
- Formal thought disorder in schizophrenia ( 22648509
)
- HDL cholesterol levels ( 32109663
32203549
)
- Hip circumference adjusted for BMI ( 25673412
)
- Liver enzyme levels (alanine transaminase) ( 33972514
)
- Lung function (forced vital capacity) ( 24929828
)
- Macular thickness ( 30535121
)
- Metabolite levels ( 23823483
)
- Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808
)
- Obesity-related traits ( 23251661
)
- Primary tooth development (number of teeth) ( 20195514
23704328
)
- Primary tooth development (time to first tooth eruption) ( 20195514
23704328
)
- Prudent dietary pattern ( 28644415
)
- Pulmonary function (smoking interaction) ( 23284291
)
- QT interval ( 19305409
29874175
30679814
24952745
)
- Refractive error ( 23396134
)
- Renal overload gout ( 32238385
)
- Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1) ( 26503814
)
- Spherical equivalent (joint analysis main effects and education interaction) ( 27020472
)
- Spherical equivalent or myopia (age of diagnosis) ( 29808027
)
- T wave morphology restitution during exercise ( 31607149
)
- T wave morphology restitution during exercise (MTAG) ( 31607149
)
- Thyrotoxic hypokalemic periodic paralysis ( 22863731
22399142
)
- Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781
)
- Thyrotoxic periodic paralysis ( 33105104
)
- TPE interval (response to exercise) ( 32386560
)
- TPE interval (resting) ( 32386560
)
- Triglyceride levels ( 32203549
)
- Waist-to-hip ratio adjusted for BMI ( 26426971
)
- Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625
)
- Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500
)
- Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500
)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971
)
- Waist-to-hip ratio adjusted for body mass index ( 25673412
28448500
)
- White matter hyperintensity volume ( 33293549
)
- White matter hyperintensity volume (adjusted for hypertension) ( 33293549
)
|
- Birth weight ( 31043758
)
- Body mass index ( 26426971
)
- Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872
)
- Metabolite levels ( 23823483
)
- Palmitoleic acid (16:1n-7) levels ( 23362303
)
- Periodontitis (DPAL) ( 24024966
)
- Primary tooth development (number of teeth) ( 23704328
)
- Primary tooth development (time to first tooth eruption) ( 23704328
)
- Serum metabolite levels ( 25569235
)
- Thyrotoxic hypokalemic periodic paralysis ( 22863731
)
- Waist-to-hip ratio adjusted for BMI ( 26426971
)
- Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971
)
|
| Novel Interactors |
1 novel interactors:
UTP18
|
None recorded
|
| Interacting Genes |
20 interacting genes:
AKAP5
ARL13B
CASK
DLG1
DLG2
DLG3
DLG4
FLNA
IL16
KCNJ11
KCNJ15
KCNJ16
KCNJ18
KCNJ4
KCNJ8
PATJ
SDC3
SDCBP
SEC22A
TRAK2
|
4 interacting genes:
KCNJ10
KCNJ15
KCNJ2
NEDD4
|
| Entrez ID |
3759 |
3773 |
| HPRD ID |
02815
|
16146
|
| Ensembl ID |
ENSG00000123700
|
ENSG00000153822
|
| Uniprot IDs |
P63252
|
A8K434
Q8N538
Q9NPI9
|
| PDB IDs |
6SPZ
7ZDZ
8QQL
|
Not available
|
| GO Terms Enriched among Interactors |
|
|