KCNJ16 and KCNJ10

Number of citations of the paper that reports this interaction (PubMedID 12456399)
0

Data Source:
HPRD (in vitro)

		KCNJ16	KCNJ10
Description		potassium inwardly rectifying channel subfamily J member 16	potassium inwardly rectifying channel subfamily J member 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Basolateral Plasma Membrane Monoatomic Ion Channel Complex	Plasma Membrane Membrane Basolateral Plasma Membrane Monoatomic Ion Channel Complex Cell Body Astrocyte Projection Ciliary Base Presynapse
	Molecular Function	Inward Rectifier Potassium Channel Activity	Nucleotide Binding Inward Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding ATP Binding ATP-activated Inward Rectifier Potassium Channel Activity
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Potassium Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Monoatomic Ion Transport Potassium Ion Transport Visual Perception Adult Walking Behavior Oligodendrocyte Development Central Nervous System Myelination Metal Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Cellular Response To Potassium Ion Regulation Of Membrane Potential Regulation Of Long-term Neuronal Synaptic Plasticity Establishment Of Localization In Cell Glutamate Reuptake Potassium Ion Homeostasis Regulation Of Resting Membrane Potential Potassium Ion Transmembrane Transport Non-motile Cilium Assembly Potassium Ion Import Across Plasma Membrane
Pathways		Activation of G protein gated Potassium channels Potassium transport channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	Activation of G protein gated Potassium channels Potassium transport channels Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
Drugs			Ritodrine Yohimbine Butamben
Diseases			Seizures-sensorineural deafness-ataxia-mental retardation-electrolyte imbalance (SESAME) ; SeSAME/EAST syndrome
GWAS		Birth weight ( 31043758) Body mass index ( 26426971) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Metabolite levels ( 23823483) Palmitoleic acid (16:1n-7) levels ( 23362303) Periodontitis (DPAL) ( 24024966) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328) Serum metabolite levels ( 25569235) Thyrotoxic hypokalemic periodic paralysis ( 22863731) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		4 interacting genes: KCNJ10 KCNJ15 KCNJ2 NEDD4	9 interacting genes: APP DLG1 DLG4 IL16 KCNJ16 PATJ SIAH1 SNCA SNTA1
Entrez ID		3773	3766
HPRD ID		16146	03732
Ensembl ID		ENSG00000153822	ENSG00000177807
Uniprot IDs		A8K434 Q8N538 Q9NPI9	P78508
PDB IDs
Enriched GO Terms of Interacting Partners?		Inward Rectifier Potassium Channel Activity Regulation Of Monoatomic Ion Transmembrane Transport Potassium Ion Import Across Plasma Membrane Regulation Of Monoatomic Ion Transport Inorganic Cation Import Across Plasma Membrane Import Into Cell Metal Ion Transport Monoatomic Ion Channel Complex Import Across Plasma Membrane Potassium Ion Transmembrane Transport Regulation Of Resting Membrane Potential Monoatomic Cation Transport Potassium Ion Transport Monoatomic Ion Transport Potassium Ion Homeostasis Regulation Of Membrane Potential Regulation Of Transport Regulation Of Potassium Ion Transmembrane Transport Potassium Channel Activity Regulation Of Potassium Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential Formation Of Structure Involved In A Symbiotic Process Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport Relaxation Of Skeletal Muscle Glutamate Reuptake Channel Inhibitor Activity Phosphothreonine Residue Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Transmembrane Transport Nuclear Receptor-mediated Corticosteroid Signaling Pathway Regulation Of Monoatomic Cation Transmembrane Transport ATP-activated Inward Rectifier Potassium Channel Activity Phosphoserine Residue Binding Beta-2 Adrenergic Receptor Binding Negative Regulation Of Potassium Ion Export Across Plasma Membrane Sodium Channel Inhibitor Activity Response To Metal Ion Potassium Channel Inhibitor Activity Regulation Of Metal Ion Transport L-glutamate Import Across Plasma Membrane Relaxation Of Cardiac Muscle Central Nervous System Myelination Astrocyte Projection Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway	Regulation Of Monoatomic Ion Transport Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Monoatomic Ion Transmembrane Transport Amyloid Fibril Formation Regulation Of Metal Ion Transport Regulation Of Membrane Potential Regulation Of Transport Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Apical/basal Cell Polarity Regulation Of Neuronal Synaptic Plasticity NMDA Selective Glutamate Receptor Signaling Pathway Synaptic Membrane Regulation Of Monoatomic Cation Transmembrane Transport Neuromuscular Junction Chemical Synaptic Transmission Trans-synaptic Signaling Acetylcholine Receptor Binding Synaptic Signaling Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Synaptic Transmission Regulation Of Neurotransmitter Uptake Cell Junction Organization Cellular Response To Copper Ion Establishment Or Maintenance Of Cell Polarity Regulation Of Presynapse Organization Positive Regulation Of Inflammatory Response Regulation Of Presynapse Assembly Cellular Response To Metal Ion Supramolecular Fiber Organization Ionotropic Glutamate Receptor Signaling Pathway Microglial Cell Activation Ionotropic Glutamate Receptor Binding Locomotory Behavior Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of System Process Leukocyte Activation Involved In Inflammatory Response Protein Localization To Postsynaptic Membrane Cell Junction Protein Localization To Postsynapse Regulation Of Synaptic Plasticity Response To Copper Ion Plasma Membrane Cell-cell Signaling Regulation Of Sodium Ion Transmembrane Transport Regulation Of Calcium Ion Transport Presynapse Postsynapse Ligand-gated Ion Channel Signaling Pathway Signaling Regulation Of Cell Activation
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