KCNJ1 and GOLGA3

Number of citations of the paper that reports this interaction (PMID 16543716)
6

Data Source:
HPRD (in vivo, two hybrid)

		KCNJ1	GOLGA3
Gene Name		potassium channel, inwardly rectifying subfamily J, member 1	golgin A3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex	Golgi Membrane Nucleus Nucleoplasm Nucleolus Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane Golgi Transport Complex Golgi Cisterna Membrane Extrinsic Component Of Golgi Membrane
	Molecular Function	Inward Rectifier Potassium Channel Activity ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding ATP-activated Inward Rectifier Potassium Channel Activity	Transporter Activity Protein Binding
	Biological Process	Kidney Development Tissue Homeostasis Potassium Ion Transport Synaptic Transmission Excretion Post-embryonic Development Potassium Ion Import Regulation Of Ion Transmembrane Transport Renal Sodium Ion Absorption Cardiovascular System Development Regulation Of G-protein Activated Inward Rectifier Potassium Channel Activity	Intra-Golgi Vesicle-mediated Transport
Pathways		Inwardly rectifying K+ channels Potassium transport channels Potassium Channels
Drugs		Bethanidine Glimepiride Minoxidil Acetohexamide Tolazamide Glyburide Tolbutamide Glycodiazine Agmatine
Diseases
GWAS			Immune response to smallpox vaccine (IL-6) ( 22542470)
Protein-Protein Interactions		8 interactors: GOLGA3 IL16 PRKCD SGK1 SH3RF1 SLC9A3R1 SLC9A3R2 UBC	8 interactors: ATXN7 CASP2 CASP3 CASP7 GOLGA7 GOPC KCNJ1 TSNAX
Entrez ID		3758	2802
HPRD ID		08981	03990
Ensembl ID		ENSG00000151704	ENSG00000090615
Uniprot IDs		A8K432 P48048	Q08378
PDB IDs
Enriched GO Terms of Interacting Partners?		Renal Sodium Ion Transport Renal Absorption Negative Regulation Of Signal Transduction Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Negative Regulation Of Signaling Regulation Of MAPK Cascade Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Intracellular Signal Transduction Positive Regulation Of Transporter Activity Apoptotic Process Programmed Cell Death Cell Death Death Negative Regulation Of Intracellular Signal Transduction Renal Phosphate Ion Absorption Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Catalytic Activity Renal System Process Regulation Of Phosphorylation Negative Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Phospholipid Catabolic Process Glutathione Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cell Death Regulation Of Signal Transduction Interleukin-10 Production Regulation Of Locomotion Negative Regulation Of MAPK Cascade Epidermal Growth Factor Receptor Signaling Pathway Renal Sodium Ion Absorption Negative Regulation Of Filopodium Assembly Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Signaling Regulation Of Protein Kinase Activity Interleukin-12 Production Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Catalytic Activity Response To Fibroblast Growth Factor Regulation Of Kinase Activity Positive Regulation Of Apoptotic Signaling Pathway Cellular Phosphate Ion Homeostasis Positive Regulation Of Ceramide Biosynthetic Process Regulation Of Sodium:proton Antiporter Activity	Execution Phase Of Apoptosis Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Intrinsic Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Protein Processing Golgi To Plasma Membrane Transport Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Apoptotic Signaling Pathway Positive Regulation Of Neuron Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of Endopeptidase Activity Regulation Of Peptidase Activity Positive Regulation Of Neuron Death Cytoplasmic Sequestering Of CFTR Protein Regulation Of G-protein Activated Inward Rectifier Potassium Channel Activity Post-Golgi Vesicle-mediated Transport Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Extrinsic Apoptotic Signaling Pathway Zymogen Activation Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Nucleus Organization Positive Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Endopeptidase Activity Positive Regulation Of Cell Death Regulation Of Inward Rectifier Potassium Channel Activity Positive Regulation Of Peptidase Activity Regulation Of Proteolysis Renal Sodium Ion Absorption Renal Sodium Ion Transport Luteolysis Peptidyl-L-cysteine S-palmitoylation Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Golgi To Plasma Membrane Protein Transport Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Glial Cell Apoptotic Process Neurotrophin Signaling Pathway Regulation Of Apoptotic DNA Fragmentation Regulation Of Neuron Apoptotic Process Regulation Of Golgi To Plasma Membrane Protein Transport Apoptotic Process Golgi Vesicle Transport Programmed Cell Death Reproduction Regulation Of Neuron Death
Tagcloud ?		2cl a198t ante antenatal ascending ba2 bartter cdnas cos cotransport currents d108h henle infrequently inwardly kir mg2 p110l potassium reabsorption rectifying romk romk1 salt talh v315g v72e wasting wildtype
Tagcloud (Difference) ?		2cl a198t ante antenatal ascending ba2 bartter cdnas cos cotransport currents d108h henle infrequently inwardly kir mg2 p110l potassium reabsorption rectifying romk romk1 salt talh v315g v72e wasting wildtype
Tagcloud (Intersection) ?