KCNG3 and KCNC1

Number of citations of the paper that reports this interaction (PubMedID 12060745)
35

Data Source:
HPRD (two hybrid)

		KCNG3	KCNC1
Description		potassium voltage-gated channel modifier subfamily G member 3	potassium voltage-gated channel subfamily C member 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Monoatomic Ion Channel Complex	Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Membrane Axon Dendrite Axolemma Neuron Projection Membrane Dendrite Membrane Neuronal Cell Body Membrane Monoatomic Ion Channel Complex Presynaptic Membrane Cell Projection Neuronal Cell Body Axon Terminus Calyx Of Held Synapse Postsynaptic Membrane
	Molecular Function	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity	Monoatomic Ion Channel Activity Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Potassium Channel Activity Protein Binding Kinesin Binding Gated Channel Activity Transmembrane Transporter Binding Voltage-gated Monoatomic Ion Channel Activity Involved In Regulation Of Presynaptic Membrane Potential
	Biological Process	Action Potential Monoatomic Ion Transport Potassium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transport Protein Homooligomerization Transmembrane Transport Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport	Action Potential Monoatomic Ion Transport Potassium Ion Transport Response To Toxic Substance Response To Light Intensity Response To Auditory Stimulus Response To Amine Cerebellum Development Optic Nerve Development Globus Pallidus Development Corpus Callosum Development Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Response To Potassium Ion Protein Homooligomerization Protein Tetramerization Transmembrane Transport Cellular Response To Xenobiotic Stimulus Response To Fibroblast Growth Factor Potassium Ion Transmembrane Transport Regulation Of Presynaptic Membrane Potential Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transport Response To Nerve Growth Factor
Pathways		Voltage gated Potassium channels	Voltage gated Potassium channels
Drugs		Enflurane Promethazine Miconazole	Enflurane Promethazine Miconazole Dalfampridine
Diseases
GWAS		Body mass index ( 25673413) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Thrombosis ( 26908601)	Body mass index ( 26426971) Night sleep phenotypes ( 27126917) Opioid sensitivity ( 24143882)
Interacting Genes		4 interacting genes: KCNB1 KCNB2 KCNC1 KCNF1	7 interacting genes: ANK3 KCNG3 KCNH1 KCNV2 LPAR3 TMBIM6 TRARG1
Entrez ID		170850	3746
HPRD ID		16232	15936
Ensembl ID		ENSG00000171126	ENSG00000129159
Uniprot IDs		Q8TAE7	P48547
PDB IDs			7PHH 7PHI 7PHK 7PHL 7PQT 7PQU 8F1C 8F1D 8QUC 8QUD
Enriched GO Terms of Interacting Partners?		Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Action Potential Delayed Rectifier Potassium Channel Activity Monoatomic Ion Channel Complex Neuronal Cell Body Membrane Potassium Ion Transmembrane Transport Monoatomic Ion Channel Activity Potassium Ion Transport Protein Homooligomerization Potassium Channel Regulator Activity Protein Complex Oligomerization Regulation Of Membrane Potential Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Inorganic Ion Transmembrane Transport Dendrite Membrane Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Monoatomic Ion Transport Non-motile Cilium Assembly Neuronal Cell Body Transmembrane Transport Cellular Component Assembly Dendrite Cell Projection Protein-containing Complex Assembly Regulation Of Potassium Ion Transport Localization Within Membrane Protein-containing Complex Organization Transmembrane Transporter Binding Perikaryon Regulation Of Transport Positive Regulation Of Norepinephrine Secretion Globus Pallidus Development Gated Channel Activity Neuron Projection Membrane Regulation Of Centriole-centriole Cohesion Clustering Of Voltage-gated Potassium Channels Intracellular Protein Localization Protein Localization To Plasma Membrane Positive Regulation Of Long-term Synaptic Depression Positive Regulation Of Protein Localization To Centrosome Protein Localization To Cell Periphery Postsynaptic Membrane Proximal Dendrite Cholesterol Catabolic Process Cilium Assembly	Voltage-gated Potassium Channel Activity Potassium Channel Activity Voltage-gated Potassium Channel Complex Regulation Of Metal Ion Transport Action Potential Regulation Of Membrane Potential Regulation Of Monoatomic Ion Transport Monoatomic Ion Channel Complex Potassium Ion Transmembrane Transport Transmembrane Transport Monoatomic Ion Channel Activity Potassium Ion Transport Metal Ion Transport Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Regulation Of Biological Quality Plasma Membrane Inorganic Ion Transmembrane Transport Regulation Of Monoatomic Cation Transmembrane Transport Monoatomic Cation Transport Monoatomic Ion Transmembrane Transport Potassium Channel Regulator Activity Regulation Of Monoatomic Ion Transmembrane Transport Establishment Of Protein Localization To Plasma Membrane Monoatomic Ion Transport Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Cation Transmembrane Transport Axon Negative Regulation Of Monoatomic Ion Transmembrane Transport Cyclic Nucleotide Binding Neuron Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Regulation Of Potassium Ion Transport Negative Regulation Of Monoatomic Ion Transport Positive Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Maintenance Of Protein Location In Plasma Membrane Endoribonuclease Inhibitor Activity Negative Regulation Of Transmembrane Transport Positive Regulation Of Cell Communication By Electrical Coupling Vesicle-mediated Transport To The Plasma Membrane Membrane Lysophosphatidic Acid Receptor Activity Regulation Of Transport Cellular Response To Metal Ion Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Negative Regulation Of Calcium Ion Transport Into Cytosol Cellular Response To Magnesium Ion Positive Regulation Of Monoatomic Ion Transport Negative Regulation Of IRE1-mediated Unfolded Protein Response Glucose Import In Response To Insulin Stimulus Protein Localization To Plasma Membrane
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