ITGA7 and FHL3

Number of citations of the paper that reports this interaction (PMID 15117962)
20

Data Source:
BioGRID (imaging technique)
HPRD (in vitro, in vivo, two hybrid)

		ITGA7	FHL3
Gene Name		integrin, alpha 7	four and a half LIM domains 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Muscle Tendon Junction Cell Surface Neuromuscular Junction Integrin Alpha7-beta1 Complex Sarcolemma	Stress Fiber Nucleus Focal Adhesion Z Disc
	Molecular Function	Integrin Binding Laminin Binding Metal Ion Binding Protein Heterodimerization Activity	Actin Binding Zinc Ion Binding
	Biological Process	Cell-matrix Adhesion Integrin-mediated Signaling Pathway Muscle Organ Development Skeletal Muscle Tissue Development Regulation Of Cell Shape Cell Migration Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Endodermal Cell Differentiation Blood Vessel Morphogenesis	Muscle Organ Development Actin Cytoskeleton Organization
Pathways		Laminin interactions ECM proteoglycans Integrin cell surface interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: CHRNA1 FHL2 FHL3 MYOC	88 interactors: A1CF ACTB ADAM15 ADAMTSL4 AIMP2 AMBP C14orf105 C9orf116 CDC25B CDC42EP1 CNNM3 CORO1A CSF1 CTBP2 DCDC2B E2F8 EFCAB12 EPHA10 EPM2AIP1 FAM154A FAM71C FAM90A1 FBXL18 FHL2 FHL5 FOSL2 GATA2 GCM2 HIPK1 HYAL2 ITGA7 KIRREL2 KLF3 KLF8 KRTAP12-1 KRTAP12-2 KTI12 LASP1 LMO2 LNX1 MAPK1 MED15 MPZL1 MRPL27 MYBPC1 MYBPHL MZF1 NPRL3 P4HA2 PAK7 PATL1 PHC2 PHF21A PLEKHF2 PPIG PTPN6 QRICH1 RAD21 RBM42 RFX3 RFX6 RHEBL1 RNMTL1 SAP30BP SLAIN1 SLC25A46 SLC44A3 SMAD2 SMAD3 SMAD4 SNRPG SREBF2 SRF TMX3 TRAF3IP2 TRIM27 TRIP6 TRO TTLL10 TYK2 TYMSOS UBE2I UBE2Q1 WNK1 YPEL3 ZNF417 ZNF512B ZNRD1
Entrez ID		3679	2275
HPRD ID		02761	09101
Ensembl ID		ENSG00000135424	ENSG00000183386
Uniprot IDs		J3KNV4 Q13683 Q4LE35	Q13643 Q96C98
PDB IDs			1WYH 2CUQ 2EHE
Enriched GO Terms of Interacting Partners?		Muscle Structure Development Skeletal Muscle Hypertrophy ERBB2-ERBB3 Signaling Pathway Osteoblast Differentiation Organ Development ERBB2 Signaling Pathway Atrial Cardiac Muscle Cell Development Skeletal Muscle Tissue Growth Muscle System Process Muscle Organ Development Ossification Non-canonical Wnt Signaling Pathway Via JNK Cascade System Development Striated Muscle Tissue Development Neuron Cellular Homeostasis Non-canonical Wnt Signaling Pathway Via MAPK Cascade Muscle Tissue Development Clustering Of Voltage-gated Sodium Channels Skeletal Muscle Adaptation Positive Regulation Of Mitochondrial Depolarization Multicellular Organismal Development Negative Regulation Of Stress Fiber Assembly Anatomical Structure Development Neuronal Ion Channel Clustering Negative Regulation Of Actin Filament Bundle Assembly Heart Trabecula Formation Developmental Process Regulation Of Mitochondrial Depolarization Ventricular Cardiac Muscle Cell Development Negative Regulation Of Rho Protein Signal Transduction Neuromuscular Synaptic Transmission Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Muscle Cell Cellular Homeostasis Heart Trabecula Morphogenesis Muscle Hypertrophy Ventricular Cardiac Muscle Cell Differentiation Skeletal Muscle Contraction Neuron Maturation Neuronal Action Potential Non-canonical Wnt Signaling Pathway Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Membrane Depolarization Negative Regulation Of Cell-matrix Adhesion Androgen Receptor Signaling Pathway Musculoskeletal Movement Positive Regulation Of Stress Fiber Assembly Myelination In Peripheral Nervous System Regulation Of Focal Adhesion Assembly	RNA Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process SMAD Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Proliferation Negative Regulation Of RNA Biosynthetic Process Tissue Development Positive Regulation Of Cellular Metabolic Process Cell Death Death Multicellular Organismal Homeostasis Positive Regulation Of Epithelial To Mesenchymal Transition Endoderm Development Negative Regulation Of Cell Growth Embryonic Organ Development Positive Regulation Of Metabolic Process Primary MiRNA Processing Organ Development Apoptotic Process
Tagcloud ?			accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1
Tagcloud (Difference) ?			accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1
Tagcloud (Intersection) ?