KRTAP12-2 and NPDC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP12-2	NPDC1
Description		keratin associated protein 12-2	neural proliferation, differentiation and control 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways		Keratinization	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS			Lymphocyte count ( 27863252) Monocyte percentage of white cells ( 27863252 32888494) White blood cell count ( 27863252 32888494)
Interacting Genes		127 interacting genes: ADAM12 ARID5A ATN1 ATP6V1C2 AVPI1 BCL6B BEX2 CATSPER1 CBLL2 CBX2 CCNL1 CCNL2 CFP CHRD CNNM3 CYSRT1 DGCR6 DHRS1 EFEMP2 ETNK2 FAM27E3 FHL3 FOXD4 FOXD4L1 FOXD4L3 GDF15 GPANK1 GPRIN2 GREM1 HOXA1 HOXB9 HSFX1 HSFX2 HYPK INO80B IQUB KRT34 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1F LCE2A LCE2B LCE4A LCE5A LINC00671 MEOX2 MGAT5B MYOZ1 MYPOP NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR1D2 ODF1 OTX1 PACSIN3 PATZ1 PCSK5 PDE9A PELO PHLDA1 PIH1D2 PLAC8 POLR1C POM121L8P POU4F2 RAD23A RBM39 RBPMS RBX1 RHOXF2 SEMA3B SLC12A4 SLC13A5 SLC15A2 SLC15A3 SPATA3 SPMIP9 SPRED2 SPRY1 SRSF8 TCEA2 TINAGL1 TLE5 TMEM179B TNS2 TRIM42 TRIP13 TSGA10IP TTPA VASN VENTX VGLL3 YIPF3 YY1 ZBTB9 ZDHHC1 ZIM2 ZNF100 ZNF408 ZNF497 ZNF581 ZNF587 ZNF624 ZNF688 ZNF696 ZNF764 ZNF785 ZNHIT1	41 interacting genes: C3orf52 CCND1 CCND2 CCND3 CDK2 CPT1A CYSRT1 E2F1 EMD FHL5 HINFP HNRNPK KHDRBS2 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP4-1 KRTAP4-12 KRTAP4-4 KRTAP5-9 KRTAP9-3 MADD MAL MDFI MS4A13 NBPF19 NOTCH2NLA PLSCR1 RBMY1F RBMY1J TFDP1
Entrez ID		353323	56654
HPRD ID		11198	12048
Ensembl ID		ENSG00000221864	ENSG00000107281
Uniprot IDs		P59991	Q9NQX5
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Sequence-specific DNA Binding Tissue Development Regulation Of Nucleobase-containing Compound Metabolic Process Peptidoglycan Transport Identical Protein Binding Peptide:proton Symporter Activity Dipeptide Transmembrane Transporter Activity Negative Regulation Of Lens Fiber Cell Differentiation Dipeptide Transmembrane Transport Dipeptide Import Across Plasma Membrane Dipeptide Transport	Intermediate Filament Keratin Filament Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Cyclin-dependent Protein Serine/threonine Kinase Activator Activity Cyclin-dependent Protein Kinase Holoenzyme Complex Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle G1/S Phase Transition Cytosol Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Negative Regulation Of Fat Cell Proliferation Rb-E2F Complex Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Phase Transition DNA Damage Checkpoint Signaling Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Process Regulation Of MRNA Processing Anoikis Positive Regulation Of Cell Cycle Process Signal Transduction In Response To DNA Damage Hair Cycle Protein Serine/threonine Kinase Activator Activity Identical Protein Binding Mitotic G1 DNA Damage Checkpoint Signaling Mitotic G1/S Transition Checkpoint Signaling Regulation Of Cell Cycle Regulation Of RNA Splicing Positive Regulation Of Cell Cycle Regulation Of MRNA Metabolic Process Regulation Of Mitotic Cell Cycle Microtubule Organizing Center Response To X-ray Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Cell Cycle Phase Transition Liver Regeneration TMEM240-body Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane
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