KRTAP12-2 and CCNL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP12-2	CCNL2
Description		keratin associated protein 12-2	cyclin L2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Cyclin-dependent Protein Kinase Holoenzyme Complex Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Protein Binding	Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process		Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of Centrosome Cycle Regulation Of Cell Cycle
Pathways		Keratinization
Drugs
Diseases
GWAS			Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908)
Interacting Genes		127 interacting genes: ADAM12 ARID5A ATN1 ATP6V1C2 AVPI1 BCL6B BEX2 CATSPER1 CBLL2 CBX2 CCNL1 CCNL2 CFP CHRD CNNM3 CYSRT1 DGCR6 DHRS1 EFEMP2 ETNK2 FAM27E3 FHL3 FOXD4 FOXD4L1 FOXD4L3 GDF15 GPANK1 GPRIN2 GREM1 HOXA1 HOXB9 HSFX1 HSFX2 HYPK INO80B IQUB KRT34 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1F LCE2A LCE2B LCE4A LCE5A LINC00671 MEOX2 MGAT5B MYOZ1 MYPOP NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR1D2 ODF1 OTX1 PACSIN3 PATZ1 PCSK5 PDE9A PELO PHLDA1 PIH1D2 PLAC8 POLR1C POM121L8P POU4F2 RAD23A RBM39 RBPMS RBX1 RHOXF2 SEMA3B SLC12A4 SLC13A5 SLC15A2 SLC15A3 SPATA3 SPMIP9 SPRED2 SPRY1 SRSF8 TCEA2 TINAGL1 TLE5 TMEM179B TNS2 TRIM42 TRIP13 TSGA10IP TTPA VASN VENTX VGLL3 YIPF3 YY1 ZBTB9 ZDHHC1 ZIM2 ZNF100 ZNF408 ZNF497 ZNF581 ZNF587 ZNF624 ZNF688 ZNF696 ZNF764 ZNF785 ZNHIT1	15 interacting genes: CDK11B DYRK1A EMD FAM90A1 KRTAP12-2 MAGEB2 MDFI PIH1D2 POLR2A RUNDC3A SRSF2 SRSF7 TRIM41 USP20 ZBTB7B
Entrez ID		353323	81669
HPRD ID		11198	10815
Ensembl ID		ENSG00000221864	ENSG00000221978
Uniprot IDs		P59991	Q96S94
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Sequence-specific DNA Binding Tissue Development Regulation Of Nucleobase-containing Compound Metabolic Process Peptidoglycan Transport Identical Protein Binding Peptide:proton Symporter Activity Dipeptide Transmembrane Transporter Activity Negative Regulation Of Lens Fiber Cell Differentiation Dipeptide Transmembrane Transport Dipeptide Import Across Plasma Membrane Dipeptide Transport	Regulation Of RNA Splicing Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Positive Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process Histone H3T45 Kinase Activity TMEM240-body Negative Regulation Of NK T Cell Proliferation
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