KRTAP12-2 and FAM27E3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		KRTAP12-2	FAM27E3
Description		keratin associated protein 12-2	family with sequence similarity 27 member E3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament
	Molecular Function	Protein Binding	Protein Binding
	Biological Process
Pathways		Keratinization
Drugs
Diseases
GWAS
Interacting Genes		127 interacting genes: ADAM12 ARID5A ATN1 ATP6V1C2 AVPI1 BCL6B BEX2 CATSPER1 CBLL2 CBX2 CCNL1 CCNL2 CFP CHRD CNNM3 CYSRT1 DGCR6 DHRS1 EFEMP2 ETNK2 FAM27E3 FHL3 FOXD4 FOXD4L1 FOXD4L3 GDF15 GPANK1 GPRIN2 GREM1 HOXA1 HOXB9 HSFX1 HSFX2 HYPK INO80B IQUB KRT34 KRTAP10-5 KRTAP10-8 KRTAP12-1 KRTAP12-4 KRTAP13-2 KRTAP15-1 KRTAP19-2 KRTAP21-2 KRTAP26-1 KRTAP3-2 KRTAP4-2 KRTAP5-9 KRTAP6-2 KRTAP6-3 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1F LCE2A LCE2B LCE4A LCE5A LINC00671 MEOX2 MGAT5B MYOZ1 MYPOP NBPF19 NECTIN2 NOTCH2NLA NPDC1 NR1D2 ODF1 OTX1 PACSIN3 PATZ1 PCSK5 PDE9A PELO PHLDA1 PIH1D2 PLAC8 POLR1C POM121L8P POU4F2 RAD23A RBM39 RBPMS RBX1 RHOXF2 SEMA3B SLC12A4 SLC13A5 SLC15A2 SLC15A3 SPATA3 SPMIP9 SPRED2 SPRY1 SRSF8 TCEA2 TINAGL1 TLE5 TMEM179B TNS2 TRIM42 TRIP13 TSGA10IP TTPA VASN VENTX VGLL3 YIPF3 YY1 ZBTB9 ZDHHC1 ZIM2 ZNF100 ZNF408 ZNF497 ZNF581 ZNF587 ZNF624 ZNF688 ZNF696 ZNF764 ZNF785 ZNHIT1	10 interacting genes: APP CCDC85B KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP4-12 MDFI PRNP
Entrez ID		353323	100131997
HPRD ID		11198
Ensembl ID		ENSG00000221864
Uniprot IDs		P59991
PDB IDs
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Epidermis Development Protein Binding Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Sequence-specific DNA Binding Tissue Development Regulation Of Nucleobase-containing Compound Metabolic Process Peptidoglycan Transport Identical Protein Binding Peptide:proton Symporter Activity Dipeptide Transmembrane Transporter Activity Negative Regulation Of Lens Fiber Cell Differentiation Dipeptide Transmembrane Transport Dipeptide Import Across Plasma Membrane Dipeptide Transport	Intermediate Filament Keratin Filament Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Long-term Synaptic Potentiation Intracellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Response To Copper Ion Molecular Function Activator Activity Response To Copper Ion Neuron Projection Organization Regulation Of Long-term Synaptic Potentiation Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Positive Regulation Of Calcium-mediated Signaling Amylin Binding Response To Amyloid-beta Positive Regulation Of Toll Signaling Pathway Cellular Response To Amyloid-beta Type 8 Metabotropic Glutamate Receptor Binding Positive Regulation Of Neuron Apoptotic Process Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Calcium-mediated Signaling Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Identical Protein Binding Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Type II Interferon Production Cellular Response To Norepinephrine Stimulus Memory Cytosol Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Type 5 Metabotropic Glutamate Receptor Binding Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation
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