TUBB2B and C8orf33

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TUBB2B	C8orf33
Gene Name		tubulin, beta 2B class IIb	chromosome 8 open reading frame 33
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process	Neuron Migration Protein Folding Microtubule-based Process Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization Transmembrane Transport
Pathways		Transport of connexons to the plasma membrane Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Hedgehog 'off' state Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane G2/M Transition L1CAM interactions Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Intraflagellar transport M Phase Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Post-chaperonin tubulin folding pathway Gap junction trafficking and regulation MHC class II antigen presentation Recruitment of mitotic centrosome proteins and complexes Orphan transporters Protein folding Gap junction assembly Gap junction trafficking Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Chaperonin-mediated protein folding Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ANXA7 BID C8orf33 CACNA1A CDKN1A CENPU CSNK2B HDAC6 RGS2 RPL35	41 interactors: AAMP ALAS1 APP BLOC1S2 BRD4 CEP70 CRELD2 DVL3 EDRF1 EPS8 FAM9B FEZ1 FST FYN GIT1 GPRASP1 HAP1 HMBOX1 IKZF1 IMMT KBTBD7 KCTD6 KRTAP10-7 LZTS2 MDFI MRFAP1 NGEF NOL7 PI4KA PNMA1 RASSF1 SF3B2 TAOK1 TRIM23 TUBA1A TUBB2B WIZ ZC3H15 ZFP28 ZNF205 ZNF331
Entrez ID		347733	65265
HPRD ID		14707	07951
Ensembl ID		ENSG00000137285	ENSG00000182307
Uniprot IDs		Q9BVA1	Q9H7E9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Positive Regulation Of Protein Complex Assembly Regulation Of Establishment Of Protein Localization Regulation Of Protein Localization Positive Regulation Of Cellular Component Biogenesis Membrane Organization Regulation Of Protein Complex Assembly Cellular Response To Heat Protein Localization To Membrane Regulation Of Microtubule Polymerization Or Depolymerization Cellular Component Assembly Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Cerebellar Molecular Layer Development Hsp90 Deacetylation Signal Transduction In Response To DNA Damage Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Chaperone-mediated Protein Complex Assembly Vestibular Nucleus Development Polyubiquitinated Misfolded Protein Transport Response To Heat Developmental Process Regulation Of Catalytic Activity Cell Cycle Cellular Protein Localization Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Response To Organic Substance Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Cell Death Regulation Of Epithelial Cell Migration Negative Regulation Of Hydrogen Peroxide Metabolic Process Gamma-aminobutyric Acid Secretion Regulation Of Reactive Oxygen Species Metabolic Process Autophagy Regulation Of Microtubule-based Process Regulation Of Cell Death Intestinal Epithelial Cell Maturation Regulation Of Acetylcholine Secretion, Neurotransmission Response To Toxic Substance Regulation Of Protein Kinase Activity Regulation Of Adrenergic Receptor Signaling Pathway Rhythmic Synaptic Transmission Intrinsic Apoptotic Signaling Pathway Response To Temperature Stimulus	Cell Cycle Regulation Of Signal Transduction Movement Of Cell Or Subcellular Component Positive Regulation Of Metabolic Process Cytoskeleton-dependent Intracellular Transport Regulation Of Signaling Axon Cargo Transport Regulation Of Cell Cycle Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Axon Guidance Positive Regulation Of Cell Cycle Process Locomotion Positive Regulation Of Signal Transduction Ephrin Receptor Signaling Pathway Regulation Of Cellular Process Regulation Of Cell Morphogenesis Protein Polymerization Regulation Of Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of JNK Cascade Positive Regulation Of Cell Cycle Microtubule-based Process Anterograde Axon Cargo Transport Positive Regulation Of Intracellular Signal Transduction Cellular Response To Stimulus Axonogenesis Microtubule-based Transport Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Neuron Projection Development Intracellular Signal Transduction Cell Projection Organization Axon Development Cell Morphogenesis Involved In Neuron Differentiation System Development Cellular Protein Complex Assembly Generation Of Neurons Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Signal Transduction Chemotaxis Enzyme Linked Receptor Protein Signaling Pathway
Tagcloud ?		200x customized dcx depths dync1h1 exome flna funded heterotopia kif5c kinesin malformations megalencephaly mosaicism neurodevelopmental neuropsychiatric nodular pachygyria panels periventricular persons polymicrogyria read sanger somatic subcloned subcloning subcortical unequal
Tagcloud (Difference) ?		200x customized dcx depths dync1h1 exome flna funded heterotopia kif5c kinesin malformations megalencephaly mosaicism neurodevelopmental neuropsychiatric nodular pachygyria panels periventricular persons polymicrogyria read sanger somatic subcloned subcloning subcortical unequal
Tagcloud (Intersection) ?