TUBB2B

Gene Name		tubulin, beta 2B class IIb
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Microtubule
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding
	Biological Process	Neuron Migration Protein Folding Microtubule-based Process Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Protein Polymerization Transmembrane Transport
Pathways		Transport of connexons to the plasma membrane Mitotic Prometaphase Organelle biogenesis and maintenance Axon guidance Hedgehog 'off' state Separation of Sister Chromatids Translocation of GLUT4 to the plasma membrane G2/M Transition L1CAM interactions Mitotic Anaphase Recycling pathway of L1 Recruitment of NuMA to mitotic centrosomes Formation of tubulin folding intermediates by CCT/TriC Intraflagellar transport M Phase Prefoldin mediated transfer of substrate to CCT/TriC Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding Post-chaperonin tubulin folding pathway Gap junction trafficking and regulation MHC class II antigen presentation Recruitment of mitotic centrosome proteins and complexes Orphan transporters Protein folding Gap junction assembly Gap junction trafficking Kinesins Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Assembly of the primary cilium Factors involved in megakaryocyte development and platelet production Cell Cycle, Mitotic Resolution of Sister Chromatid Cohesion Chaperonin-mediated protein folding Signaling by Hedgehog Centrosome maturation Mitotic G2-G2/M phases Mitotic Metaphase and Anaphase Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: ANXA7 BID C8orf33 CACNA1A CDKN1A CENPU CSNK2B HDAC6 RGS2 RPL35
Entrez ID		347733
HPRD ID		14707
Ensembl ID		ENSG00000137285
Uniprot IDs		Q9BVA1
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Positive Regulation Of Protein Complex Assembly Regulation Of Establishment Of Protein Localization Regulation Of Protein Localization Positive Regulation Of Cellular Component Biogenesis Membrane Organization Regulation Of Protein Complex Assembly Cellular Response To Heat Protein Localization To Membrane Regulation Of Microtubule Polymerization Or Depolymerization Cellular Component Assembly Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Cerebellar Molecular Layer Development Hsp90 Deacetylation Signal Transduction In Response To DNA Damage Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Chaperone-mediated Protein Complex Assembly Vestibular Nucleus Development Polyubiquitinated Misfolded Protein Transport Response To Heat Developmental Process Regulation Of Catalytic Activity Cell Cycle Cellular Protein Localization Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Response To Organic Substance Positive Regulation Of Programmed Cell Death Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Microtubule Cytoskeleton Organization Positive Regulation Of Cell Death Regulation Of Epithelial Cell Migration Negative Regulation Of Hydrogen Peroxide Metabolic Process Gamma-aminobutyric Acid Secretion Regulation Of Reactive Oxygen Species Metabolic Process Autophagy Regulation Of Microtubule-based Process Regulation Of Cell Death Intestinal Epithelial Cell Maturation Regulation Of Acetylcholine Secretion, Neurotransmission Response To Toxic Substance Regulation Of Protein Kinase Activity Regulation Of Adrenergic Receptor Signaling Pathway Rhythmic Synaptic Transmission Intrinsic Apoptotic Signaling Pathway Response To Temperature Stimulus
Tagcloud ?		200x customized dcx depths dync1h1 exome flna funded heterotopia kif5c kinesin malformations megalencephaly mosaicism neurodevelopmental neuropsychiatric nodular pachygyria panels periventricular persons polymicrogyria read sanger somatic subcloned subcloning subcortical unequal