BCL2L13 and PPT2

Number of citations of the paper that reports this interaction (PubMedID 24706805)
34

Data Source:
BioGRID (two hybrid)

		BCL2L13	PPT2
Description		BCL2 like 13	palmitoyl-protein thioesterase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Membrane Mitochondrial Membrane	Extracellular Region Lysosome Lysosomal Lumen Extracellular Exosome
	Molecular Function	Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process	Hydrolase Activity Thiolester Hydrolase Activity Fatty Acyl-CoA Hydrolase Activity Palmitoyl Hydrolase Activity
	Biological Process	Mitophagy Oxidative Phosphorylation Apoptotic Process Mitochondrion Organization Regulation Of Apoptotic Process Fat Cell Differentiation Canonical Glycolysis	Fatty-acyl-CoA Biosynthetic Process Macromolecule Depalmitoylation
Pathways			Fatty acyl-CoA biosynthesis
Drugs
Diseases
GWAS		Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Eosinophil count ( 32888494) Granulocyte count ( 27863252) Hemoglobin levels ( 32327693) Interleukin-10 levels ( 22205395) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494)	Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655) Autism spectrum disorder or schizophrenia ( 28540026) Birth weight ( 31043758) General risk tolerance (MTAG) ( 30643258) Inflammatory bowel disease ( 28067908) Offspring birth weight ( 31043758) Oleic acid (18:1n-9) levels ( 23362303) Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid) ( 24823311) Prostate cancer ( 23535732) Pulmonary function ( 20010835) Ulcerative colitis ( 28067908)
Interacting Genes		84 interacting genes: ACP5 ADIPOQ AGTRAP AIG1 APOD APP AQP1 ARL6IP1 ARLN BAZ2B BCL9 BET1 CAMLG CD53 CDC42 CDK5R1 CERS6 CLDN19 CRB3 DEFB127 ERG28 ERMP1 ETNK2 FAM210B FUS FXYD3 FZD7 GABARAPL2 GALNT2 GAST GTF2F1 HMOX2 HNRNPK IDI1 JAGN1 JPH4 LAT LAYN LPAR3 MAL MGMT MTNR1B NDRG4 NETO2 NINJ2 NR2C2AP NRBP1 PCBP1 PLLP PLN PLP1 PLPP4 PPT2 RPN2 SH3RF3 SLC30A8 SLC35A1 SLC35G5 SMARCD3 SMIM1 SPOCK1 SQLE SRSF3 STX12 STX8 TM6SF2 TMEM128 TMEM14C TMEM242 TMEM254 TMEM51 TMEM72 TMEM86A TMEM86B TMEM97 TMUB2 TNF TNMD TRARG1 TUBB UBC UPK1B VAMP3 VAMP4	1 interacting genes: BCL2L13
Entrez ID		23786	9374
HPRD ID		09822	04486
Ensembl ID		ENSG00000099968	ENSG00000221988
Uniprot IDs		A0A087WTL4 A0A087WW80 A0A087WX97 A0A0A0MR90 A8K5Y4 B2RB43 B7Z238 B7Z737 E9PDD6 F2Z2C3 F6VJB4 Q9BXK5	A0A1U9X8D2 Q9UMR5
PDB IDs			1PJA
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Localization Within Membrane SNARE Complex Cellular Localization Response To Type II Interferon Structural Constituent Of Myelin Sheath Protein Binding Regulation Of Transport Alkenylglycerophosphocholine Hydrolase Activity Cellular Response To Type II Interferon SNAP Receptor Activity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Organelle Fusion Regulation Of Cellular Localization Phagocytic Vesicle Membrane Raft Regulation Of Chemokine Production Protein Localization To Membrane Protein Localization To Cell Periphery Vesicle Fusion Vesicle Organization Organelle Membrane Fusion Negative Regulation Of Blood Circulation Vesicle Docking Regulation Of Establishment Of Protein Localization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Protein Transport Response To Cytokine Protein Localization To Plasma Membrane Response To Peptide Positive Regulation Of Chemokine Production G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Membrane Raft Distribution Establishment Of Protein Localization To Membrane Recycling Endosome Organelle Localization By Membrane Tethering Membrane Raft Localization	Mitophagy Glycolytic Process Through Glucose-6-phosphate ADP Catabolic Process Oxidative Phosphorylation ADP Metabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Glycolytic Process Glycolytic Process Through Fructose-6-phosphate Glucose Catabolic Process Canonical Glycolysis Ribonucleoside Diphosphate Catabolic Process Pyruvate Metabolic Process Purine Ribonucleotide Catabolic Process Ribonucleoside Diphosphate Metabolic Process Autophagy Of Mitochondrion Purine Nucleotide Catabolic Process Nucleoside Diphosphate Metabolic Process Aerobic Respiration Cellular Respiration Nucleotide Catabolic Process Nicotinamide Nucleotide Metabolic Process Carbohydrate Catabolic Process Glucose Metabolic Process Nucleoside Phosphate Catabolic Process Fat Cell Differentiation Mitochondrial Membrane Monosaccharide Metabolic Process ATP Metabolic Process Carbohydrate Derivative Catabolic Process Organophosphate Catabolic Process Energy Derivation By Oxidation Of Organic Compounds Macroautophagy Hexose Metabolic Process Mitochondrion Organization Purine Ribonucleotide Metabolic Process Autophagy Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process Generation Of Precursor Metabolites And Energy Nucleobase-containing Compound Catabolic Process Purine Nucleotide Metabolic Process Carbohydrate Metabolic Process Nucleotide Metabolic Process Monocarboxylic Acid Metabolic Process Purine-containing Compound Metabolic Process Nucleoside Phosphate Metabolic Process
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