BCL2L13 and BCL9

Number of citations of the paper that reports this interaction (PubMedID 24706805)
34

Data Source:
BioGRID (two hybrid)

		BCL2L13	BCL9
Description		BCL2 like 13	BCL9 transcription coactivator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Membrane Mitochondrial Membrane	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cis-Golgi Network Sarcoplasm Beta-catenin-TCF Complex
	Molecular Function	Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process	Transcription Coactivator Activity Protein Binding Beta-catenin Binding
	Biological Process	Mitophagy Oxidative Phosphorylation Apoptotic Process Mitochondrion Organization Regulation Of Apoptotic Process Fat Cell Differentiation Canonical Glycolysis	Transcription By RNA Polymerase II Myotube Differentiation Involved In Skeletal Muscle Regeneration Wnt Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Somatic Stem Cell Population Maintenance Skeletal Muscle Cell Differentiation Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Canonical Wnt Signaling Pathway
Pathways			Formation of the beta-catenin:TCF transactivating complex Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627) Eosinophil count ( 32888494) Granulocyte count ( 27863252) Hemoglobin levels ( 32327693) Interleukin-10 levels ( 22205395) Lymphocyte percentage of white cells ( 32888494) Monocyte count ( 32888494) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252 32888494) Neutrophil percentage of white cells ( 32888494) Sum neutrophil eosinophil counts ( 27863252) White blood cell count ( 32888494)	Adult body size ( 32376654) Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU) ( 24025145) Schizophrenia (negative symptoms) ( 23382809) Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Type 2 diabetes ( 25760438)
Interacting Genes		84 interacting genes: ACP5 ADIPOQ AGTRAP AIG1 APOD APP AQP1 ARL6IP1 ARLN BAZ2B BCL9 BET1 CAMLG CD53 CDC42 CDK5R1 CERS6 CLDN19 CRB3 DEFB127 ERG28 ERMP1 ETNK2 FAM210B FUS FXYD3 FZD7 GABARAPL2 GALNT2 GAST GTF2F1 HMOX2 HNRNPK IDI1 JAGN1 JPH4 LAT LAYN LPAR3 MAL MGMT MTNR1B NDRG4 NETO2 NINJ2 NR2C2AP NRBP1 PCBP1 PLLP PLN PLP1 PLPP4 PPT2 RPN2 SH3RF3 SLC30A8 SLC35A1 SLC35G5 SMARCD3 SMIM1 SPOCK1 SQLE SRSF3 STX12 STX8 TM6SF2 TMEM128 TMEM14C TMEM242 TMEM254 TMEM51 TMEM72 TMEM86A TMEM86B TMEM97 TMUB2 TNF TNMD TRARG1 TUBB UBC UPK1B VAMP3 VAMP4	6 interacting genes: BCL2L13 CTNNB1 MAP1LC3A PYGO1 PYGO2 USP9X
Entrez ID		23786	607
HPRD ID		09822	04000
Ensembl ID		ENSG00000099968	ENSG00000116128
Uniprot IDs		A0A087WTL4 A0A087WW80 A0A087WX97 A0A0A0MR90 A8K5Y4 B2RB43 B7Z238 B7Z737 E9PDD6 F2Z2C3 F6VJB4 Q9BXK5	O00512 Q1JQ81
PDB IDs			2GL7 2VP7 2VPB 2VPD 2VPE 2VPG 3SL9 8Y0P
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Localization Within Membrane SNARE Complex Cellular Localization Response To Type II Interferon Structural Constituent Of Myelin Sheath Protein Binding Regulation Of Transport Alkenylglycerophosphocholine Hydrolase Activity Cellular Response To Type II Interferon SNAP Receptor Activity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Organelle Fusion Regulation Of Cellular Localization Phagocytic Vesicle Membrane Raft Regulation Of Chemokine Production Protein Localization To Membrane Protein Localization To Cell Periphery Vesicle Fusion Vesicle Organization Organelle Membrane Fusion Negative Regulation Of Blood Circulation Vesicle Docking Regulation Of Establishment Of Protein Localization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Protein Transport Response To Cytokine Protein Localization To Plasma Membrane Response To Peptide Positive Regulation Of Chemokine Production G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Membrane Raft Distribution Establishment Of Protein Localization To Membrane Recycling Endosome Organelle Localization By Membrane Tethering Membrane Raft Localization	Canonical Wnt Signaling Pathway Spermatid Nucleus Differentiation Beta-catenin-TCF Complex Kidney Development Germ Cell Development Wnt Signaling Pathway Mitophagy Developmental Growth Mesenchymal Stem Cell Differentiation Positive Regulation Of Determination Of Dorsal Identity Negative Regulation Of Mitotic Cell Cycle, Embryonic Beta-catenin-ICAT Complex Negative Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Reproductive Process Neuron Projection Extension Glial Cell Fate Determination Renal Inner Medulla Development Scrib-APC-beta-catenin Complex Renal Outer Medulla Development Renal Vesicle Formation Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Positive Regulation Of Branching Involved In Lung Morphogenesis Neural Plate Development Developmental Cell Growth Organelle Organization K11-linked Deubiquitinase Activity Autophagy Of Mitochondrion Nucleus Organization Spermatid Development Histone Acetyltransferase Regulator Activity Oviduct Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Fungiform Papilla Formation Beta-catenin-TCF7L2 Complex Astrocyte-dopaminergic Neuron Signaling Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Regulation Of Centriole-centriole Cohesion Embryonic Skeletal Limb Joint Morphogenesis Lung Induction Neuron Migration Catenin-TCF7L2 Complex Developmental Growth Involved In Morphogenesis Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Negative Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Acinar Cell Differentiation Positive Regulation Of Proteoglycan Biosynthetic Process Metanephros Morphogenesis Trachea Morphogenesis Regulation Of Mitotic Cell Cycle, Embryonic Glial Cell-neuron Signaling
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