ID2 and MSC

Number of citations of the paper that reports this interaction (PMID 11560778)
1

Data Source:
HPRD (two hybrid)

		ID2	MSC
Gene Name		inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	musculin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Microtubule Cytoskeleton Protein Complex	Nucleus
	Molecular Function	Protein Binding Ion Channel Binding Protein Dimerization Activity	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Metanephros Development Natural Killer Cell Differentiation Membranous Septum Morphogenesis Bundle Of His Development Transcription, DNA-templated Multicellular Organismal Development Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Oligodendrocyte Development Regulation Of Lipid Metabolic Process Olfactory Bulb Development Circadian Regulation Of Gene Expression Mammary Gland Epithelial Cell Proliferation Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Enucleate Erythrocyte Differentiation Negative Regulation Of DNA Binding Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Locomotor Rhythm Negative Regulation Of B Cell Differentiation Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Macrophage Differentiation Negative Regulation Of Neuron Differentiation Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Blood Pressure Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Cell Maturation Peyer's Patch Development Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Neuron Fate Commitment Positive Regulation Of Astrocyte Differentiation Negative Regulation Of Oligodendrocyte Differentiation Adipose Tissue Development Mammary Gland Alveolus Development Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Endodermal Digestive Tract Morphogenesis Positive Regulation Of Cell Cycle Arrest Cellular Response To Lithium Ion Positive Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Senescence Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Neural Precursor Cell Proliferation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Branchiomeric Skeletal Muscle Development Palate Development Diaphragm Development
Pathways
Drugs
Diseases
GWAS		IgE levels ( 22075330)
Protein-Protein Interactions		37 interactors: ADD1 ASB4 CDK2 ELK1 ELK3 ELK4 GATA4 HES1 HSPA5 IFI16 KDM1A LRIF1 MAPK1 MAPK3 MAPK8 MSC MYF5 MYF6 MYOD1 MYOG NEDD9 PAX2 PAX5 PAX8 PPP1CA PRMT6 RB1 RBL1 RBL2 RBM48 SUV39H1 SUV39H2 TCF12 TCF3 TCF4 TSTA3 UNC119	5 interactors: EWSR1 ID2 TCF12 TCF3 TCF4
Entrez ID		3398	9242
HPRD ID		02664	04694
Ensembl ID		ENSG00000115738	ENSG00000178860
Uniprot IDs		Q02363 Q53T66	O60682
PDB IDs		4AYA
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Muscle Structure Development Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cell Differentiation Cell Differentiation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Muscle Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Organ Development Positive Regulation Of Skeletal Muscle Fiber Development Skeletal Muscle Cell Differentiation Cell Fate Commitment Developmental Process Regulation Of Cellular Process Chromatin Modification Tissue Development Skeletal Muscle Tissue Development Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cell Development	Positive Regulation Of Neurogenesis Positive Regulation Of Cell Development Regulation Of Neuron Differentiation Peyer's Patch Development Regulation Of Neurogenesis Natural Killer Cell Differentiation Regulation Of Cell Development Positive Regulation Of Cell Differentiation Transcription, DNA-templated RNA Biosynthetic Process Embryonic Digestive Tract Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Fate Commitment Positive Regulation Of Neuron Differentiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Oligodendrocyte Development Embryonic Digestive Tract Development Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Natural Killer Cell Activation Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Somatic Stem Cell Maintenance Digestive Tract Morphogenesis Positive Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Generation Of Neurons Regulation Of Cell Differentiation Macromolecule Biosynthetic Process Muscle Structure Development Positive Regulation Of Cellular Biosynthetic Process Regulation Of Glial Cell Differentiation Oligodendrocyte Differentiation Neurogenesis Canonical Wnt Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Smooth Muscle Cell Proliferation Glial Cell Development Regulation Of Gliogenesis Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Differentiation Regulation Of Fat Cell Differentiation Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition
Tagcloud ?		basic bhlh blackfan broadly compensated competed dba declined defect diamond disrupted downregulate e47 enhancing erythroblasts erythroid globin heb helix heterodimer maturation positively precursors progenitors scf scl sequesters stimulates transfusion	abp androgen aspects carrying composed dbcamp dibutyryl displaying fifteen fsh glycoprotein heterogeneous immature incubated incubating inhibin morphologically mullerian nonpermissive sertoli sgp studying subcultures substance sulfated sv40 transferrin ultrastructurally unaffected
Tagcloud (Difference) ?		basic bhlh blackfan broadly compensated competed dba declined defect diamond disrupted downregulate e47 enhancing erythroblasts erythroid globin heb helix heterodimer maturation positively precursors progenitors scf scl sequesters stimulates transfusion	abp androgen aspects carrying composed dbcamp dibutyryl displaying fifteen fsh glycoprotein heterogeneous immature incubated incubating inhibin morphologically mullerian nonpermissive sertoli sgp studying subcultures substance sulfated sv40 transferrin ultrastructurally unaffected
Tagcloud (Intersection) ?