MSC and TCF12

Number of citations of the paper that reports this interaction (PMID 9584154)
13

Data Source:
HPRD (two hybrid)

		MSC	TCF12
Gene Name		musculin	transcription factor 12
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nuclear Chromatin Nucleus Cytoplasm RNA Polymerase II Transcription Factor Complex
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Dimerization Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Enhancer Binding BHLH Transcription Factor Binding Transcription Regulatory Region DNA Binding SMAD Binding Protein Heterodimerization Activity E-box Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Branchiomeric Skeletal Muscle Development Palate Development Diaphragm Development	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Immune Response Muscle Organ Development Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: EWSR1 ID2 TCF12 TCF3 TCF4	48 interactors: ARMC8 ASCL4 BMF C16orf45 C1orf109 C6orf165 CDKN2C CRCP CREBBP DGCR6 EDRF1 EP300 HAND1 HEXIM2 HOPX ID1 ID2 ID3 LYSMD1 MAPKBP1 MLLT6 MORN4 MSC NAGK NEUROG3 OLIG3 OSGIN1 PRSS23 PSMA1 PTF1A QARS RNASEL RUNX1T1 SOX10 SOX8 SPG21 SRI STAT5A STK16 TAF4 TAL2 TBP TCF23 TCF3 TRIM72 TSNAX TWIST2 VPS28
Entrez ID		9242	6938
HPRD ID		04694	02725
Ensembl ID		ENSG00000178860	ENSG00000140262
Uniprot IDs		O60682	B4E1W1 F5GY10 Q99081
PDB IDs			2KNH 4JOL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Neurogenesis Positive Regulation Of Cell Development Regulation Of Neuron Differentiation Peyer's Patch Development Regulation Of Neurogenesis Natural Killer Cell Differentiation Regulation Of Cell Development Positive Regulation Of Cell Differentiation Transcription, DNA-templated RNA Biosynthetic Process Embryonic Digestive Tract Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Fate Commitment Positive Regulation Of Neuron Differentiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Oligodendrocyte Development Embryonic Digestive Tract Development Regulation Of Oligodendrocyte Differentiation Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Natural Killer Cell Activation Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Somatic Stem Cell Maintenance Digestive Tract Morphogenesis Positive Regulation Of Gene Expression Cellular Macromolecule Biosynthetic Process Generation Of Neurons Regulation Of Cell Differentiation Macromolecule Biosynthetic Process Muscle Structure Development Positive Regulation Of Cellular Biosynthetic Process Regulation Of Glial Cell Differentiation Oligodendrocyte Differentiation Neurogenesis Canonical Wnt Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Smooth Muscle Cell Proliferation Glial Cell Development Regulation Of Gliogenesis Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Differentiation Regulation Of Fat Cell Differentiation Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition	Gene Expression Transcription, DNA-templated RNA Metabolic Process RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Organ Development Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Developmental Process Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process System Development Transcription From RNA Polymerase II Promoter Biosynthetic Process Anatomical Structure Development Regulation Of DNA Binding Regulation Of Binding Negative Regulation Of DNA Binding Positive Regulation Of Transcription, DNA-templated Muscle Organ Development Central Nervous System Development Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Muscle Structure Development Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Binding Rhythmic Process Regulation Of Cellular Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?		abp androgen aspects carrying composed dbcamp dibutyryl displaying fifteen fsh glycoprotein heterogeneous immature incubated incubating inhibin morphologically mullerian nonpermissive sertoli sgp studying subcultures substance sulfated sv40 transferrin ultrastructurally unaffected	cadherin cascade cd91 connexin consistently crc drastically ectopic efficiently enhancement facilitated fibronectin gap hsp90alpha ikappabalpha ikkalpha ikks invasion junction knocked mesenchymal migration motifs outgrowths repressed rhsp90alpha secreted spherical spreading
Tagcloud (Difference) ?		abp androgen aspects carrying composed dbcamp dibutyryl displaying fifteen fsh glycoprotein heterogeneous immature incubated incubating inhibin morphologically mullerian nonpermissive sertoli sgp studying subcultures substance sulfated sv40 transferrin ultrastructurally unaffected	cadherin cascade cd91 connexin consistently crc drastically ectopic efficiently enhancement facilitated fibronectin gap hsp90alpha ikappabalpha ikkalpha ikks invasion junction knocked mesenchymal migration motifs outgrowths repressed rhsp90alpha secreted spherical spreading
Tagcloud (Intersection) ?