APOBEC1 and BAG4

Number of citations of the paper that reports this interaction (PMID 14559896)
2

Data Source:
HPRD (in vitro, two hybrid, in vivo)

		APOBEC1	BAG4
Gene Name		apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	BCL2-associated athanogene 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Cytosol Plasma Membrane
	Molecular Function	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding AU-rich Element Binding	Receptor Signaling Protein Activity Protein Binding Poly(A) RNA Binding Chaperone Binding
	Biological Process	RNA Processing MRNA Processing Lipid Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Response To Gamma Radiation Gene Expression Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Regulation Of Cell Proliferation Lipoprotein Biosynthetic Process Response To Drug Lipoprotein Transport Response To Ethanol MRNA Stabilization Response To Calcium Ion Defense Response To Virus DNA Demethylation Negative Regulation Of Methylation-dependent Chromatin Silencing	Protein Folding Positive Regulation Of Fibroblast Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Peptidyl-serine Phosphorylation Intracellular Signal Transduction Negative Regulation Of Apoptotic Process Positive Regulation Of Cell Adhesion Protein Heterooligomerization Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Cellular Response To Tumor Necrosis Factor Cellular Response To Epidermal Growth Factor Stimulus Protein Localization To Plasma Membrane Negative Regulation Of MRNA Modification Ruffle Assembly Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity
Pathways		mRNA Editing: C to U Conversion mRNA Editing Formation of the Editosome
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: A1CF APOBEC2 BAG4 CELF2 DNAJB11 KPNA2 SYNCRIP	6 interactors: APOBEC1 BCL2 HSPA1A HSPA8 TNFRSF1A TNFRSF25
Entrez ID		339	9530
HPRD ID		02531	04861
Ensembl ID		ENSG00000111701	ENSG00000156735
Uniprot IDs		P41238	O95429
PDB IDs			1M62 1M7K
Enriched GO Terms of Interacting Partners?		MRNA Modification MRNA Metabolic Process MRNA Processing RNA Modification RNA Processing Negative Regulation Of MRNA Modification Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Cytokine Stimulus Cellular Nitrogen Compound Metabolic Process Cytidine To Uridine Editing RNA Metabolic Process Response To Cytokine Nitrogen Compound Metabolic Process Cellular Response To Organic Substance CRD-mediated MRNA Stabilization MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Base Conversion Or Substitution Editing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cytidine Deamination Cellular Metabolic Process Protein Folding Intracellular MRNA Localization Positive Regulation Of Fibroblast Migration Response To Organic Substance RNA Splicing Regulation Of Metabolic Process DNA Demethylation Pyrimidine Nucleoside Catabolic Process NLS-bearing Protein Import Into Nucleus Ruffle Assembly Posttranscriptional Regulation Of Gene Expression Cellular Response To Epidermal Growth Factor Stimulus MRNA Stabilization Response To Epidermal Growth Factor Regulation Of Fibroblast Migration Viral Process Gene Expression Ruffle Organization MRNA Splice Site Selection Positive Regulation Of Stress Fiber Assembly	Response To Abiotic Stimulus Response To Organic Substance Protein Refolding Response To Other Organism Response To Biotic Stimulus Response To External Stimulus Regulation Of Cellular Response To Heat Response To Virus Tumor Necrosis Factor-mediated Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Apoptotic Signaling Pathway Response To Gamma Radiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cellular Response To Heat Posttranscriptional Regulation Of Gene Expression Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Apoptotic Process MRNA Metabolic Process Cellular Response To Stress Viral Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Cell Death Negative Regulation Of Cellular PH Reduction Negative Regulation Of Fibril Organization CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Retinal Cell Programmed Cell Death Cellular Response To Tumor Necrosis Factor Extrinsic Apoptotic Signaling Pathway Response To Heat Response To Stress Response To Tumor Necrosis Factor Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Unfolded Protein Cellular Response To Stimulus Response To Cytokine Cellular Heat Acclimation Cytidine To Uridine Editing Regulation Of Protein Stability Cellular Response To Organic Substance Response To Ethanol Response To Ionizing Radiation Response To Alkaloid Regulation Of Cellular Component Organization Negative Regulation Of Cell Growth Defense Response To Virus Regulation Of Fibril Organization Negative Regulation Of Methylation-dependent Chromatin Silencing Regulation Of Retinal Cell Programmed Cell Death Positive Regulation Of Neuron Maturation Response To Organonitrogen Compound
Tagcloud ?		aid apolipoprotein atherosclerosis atherosclerotic causal coincident crosses dissecting dyslipidemia editing founder genotyped hampers haplotypes hfca hidden inbred informative mapping markov multiparental outbred qtl reconstructed renders trait triglyceride triglycerides	adenocarcinoma aid alk braf clinicopathologic define differentiated druggable fgfr fgfr1 fgfr2 fgfr3 fibroblast fourteen fusion fusions harbored kras needs nsclc relapse ret ros1 screened smokers subset tacc3 tendency verified
Tagcloud (Difference) ?		apolipoprotein atherosclerosis atherosclerotic causal coincident crosses dissecting dyslipidemia editing founder genotyped hampers haplotypes hfca hidden inbred informative mapping markov multiparental outbred qtl reconstructed renders trait triglyceride triglycerides	adenocarcinoma alk braf clinicopathologic define differentiated druggable fgfr fgfr1 fgfr2 fgfr3 fibroblast fourteen fusion fusions harbored kras needs nsclc relapse ret ros1 screened smokers subset tacc3 tendency verified
Tagcloud (Intersection) ?		aid