APOBEC1 and CELF2

Number of citations of the paper that reports this interaction (PMID 11577082)
24

Data Source:
HPRD (in vitro, in vivo)

		APOBEC1	CELF2
Gene Name		apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	CUGBP, Elav-like family member 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Cytoplasm
	Molecular Function	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding AU-rich Element Binding	Nucleotide Binding RNA Binding Poly(A) RNA Binding
	Biological Process	RNA Processing MRNA Processing Lipid Metabolic Process Response To Osmotic Stress Cytidine Deamination Response To Zinc Ion Response To Gamma Radiation Gene Expression Cytidine To Uridine Editing MRNA Modification Cellular Response To Insulin Stimulus Regulation Of Cell Proliferation Lipoprotein Biosynthetic Process Response To Drug Lipoprotein Transport Response To Ethanol MRNA Stabilization Response To Calcium Ion Defense Response To Virus DNA Demethylation Negative Regulation Of Methylation-dependent Chromatin Silencing	RNA Processing MRNA Processing Regulation Of Heart Contraction
Pathways		mRNA Editing: C to U Conversion mRNA Editing Formation of the Editosome
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: A1CF APOBEC2 BAG4 CELF2 DNAJB11 KPNA2 SYNCRIP	6 interactors: A1CF APOBEC1 APP ELAVL1 PCBP1 PTGS2
Entrez ID		339	10659
HPRD ID		02531	03964
Ensembl ID		ENSG00000111701	ENSG00000048740
Uniprot IDs		P41238	B4DIB6 B4DZ01 E9PC62 O95319
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA Modification MRNA Metabolic Process MRNA Processing RNA Modification RNA Processing Negative Regulation Of MRNA Modification Negative Regulation Of Phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase Activity Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Cytokine Stimulus Cellular Nitrogen Compound Metabolic Process Cytidine To Uridine Editing RNA Metabolic Process Response To Cytokine Nitrogen Compound Metabolic Process Cellular Response To Organic Substance CRD-mediated MRNA Stabilization MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Base Conversion Or Substitution Editing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cytidine Deamination Cellular Metabolic Process Protein Folding Intracellular MRNA Localization Positive Regulation Of Fibroblast Migration Response To Organic Substance RNA Splicing Regulation Of Metabolic Process DNA Demethylation Pyrimidine Nucleoside Catabolic Process NLS-bearing Protein Import Into Nucleus Ruffle Assembly Posttranscriptional Regulation Of Gene Expression Cellular Response To Epidermal Growth Factor Stimulus MRNA Stabilization Response To Epidermal Growth Factor Regulation Of Fibroblast Migration Viral Process Gene Expression Ruffle Organization MRNA Splice Site Selection Positive Regulation Of Stress Fiber Assembly	Cytidine To Uridine Editing Base Conversion Or Substitution Editing MRNA Processing Posttranscriptional Regulation Of Gene Expression MRNA Metabolic Process RNA Processing MRNA Modification MRNA Stabilization Regulation Of MRNA Stability Regulation Of RNA Stability Response To Radiation Maintenance Of Blood-brain Barrier Positive Regulation Of Cellular Biosynthetic Process Gene Expression Synaptic Growth At Neuromuscular Junction Learning RNA Modification Negative Regulation Of Methylation-dependent Chromatin Silencing Positive Regulation Of Fibroblast Growth Factor Production Collateral Sprouting In Absence Of Injury Regulation Of Methylation-dependent Chromatin Silencing Positive Regulation Of Platelet-derived Growth Factor Production Negative Regulation Of Synaptic Transmission, Dopaminergic Nicotinamide Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Nucleobase-containing Compound Metabolic Process Positive Regulation Of Brown Fat Cell Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Axon Choice Point Recognition Positive Regulation Of Prostaglandin Biosynthetic Process Negative Regulation Of Chromatin Silencing Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Abiotic Stimulus Learning Or Memory Regulation Of Translation Cytidine Deamination Positive Regulation Of Sprouting Angiogenesis Positive Regulation Of Synaptic Plasticity Cellular Nitrogen Compound Metabolic Process Cognition Neuron Remodeling Cellular Response To ATP Response To Fructose Positive Regulation Of Fever Generation
Tagcloud ?		aid apolipoprotein atherosclerosis atherosclerotic causal coincident crosses dissecting dyslipidemia editing founder genotyped hampers haplotypes hfca hidden inbred informative mapping markov multiparental outbred qtl reconstructed renders trait triglyceride triglycerides	asset atxn1 atxn2 atxn3 atxn7 bioinformatic c5orf42 cacna1a cag crebbp ebf1 enriches melanogenesis moving nfia paxip1 plekhg4 polyq ppp2r2b sca screens spinocerebellar srsf4 stk24 tbp tremendous uguuu utrs ywhag
Tagcloud (Difference) ?		aid apolipoprotein atherosclerosis atherosclerotic causal coincident crosses dissecting dyslipidemia editing founder genotyped hampers haplotypes hfca hidden inbred informative mapping markov multiparental outbred qtl reconstructed renders trait triglyceride triglycerides	asset atxn1 atxn2 atxn3 atxn7 bioinformatic c5orf42 cacna1a cag crebbp ebf1 enriches melanogenesis moving nfia paxip1 plekhg4 polyq ppp2r2b sca screens spinocerebellar srsf4 stk24 tbp tremendous uguuu utrs ywhag
Tagcloud (Intersection) ?