APBB3 and APLP2

Number of citations of the paper that reports this interaction (PubMedID 10081969)
0

Data Source:
HPRD (in vitro)

		APBB3	APLP2
Description		amyloid beta precursor protein binding family B member 3	amyloid beta precursor like protein 2
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Actin Cytoskeleton Membrane Nuclear Body	Nucleus Endoplasmic Reticulum Lumen Plasma Membrane Membrane Platelet Alpha Granule Platelet Alpha Granule Membrane Extracellular Exosome
	Molecular Function	Amyloid-beta Binding Protein Binding Low-density Lipoprotein Particle Receptor Binding Molecular Adaptor Activity	DNA Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Heparin Binding Peptidase Inhibitor Activity Identical Protein Binding Metal Ion Binding Transition Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Positive Regulation Of Protein Secretion	G Protein-coupled Receptor Signaling Pathway Axonogenesis Central Nervous System Development
Pathways			Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Serum immune biomarker levels ( 32066700)	Blood protein levels ( 30072576)
Interacting Genes		6 interacting genes: APLP2 APP EGFR ERBB2 PDPK1 RAB4A	25 interacting genes: AKT1 APBB1 APBB2 APBB3 BRCA1 CDK1 DAB1 DAB2 DEDD ETS1 GNAO1 HGS HLA-A JUN JUNB KAT5 MAPK8 PIK3CA PRKCA PRNP RPL26 SLC13A1 UBC VKORC1 ZNF512B
Entrez ID		10307	334
HPRD ID		04089	00103
Ensembl ID		ENSG00000113108	ENSG00000084234
Uniprot IDs		O95704 Q59EH2 Q96DX9	A0A140VJE9 B4E3I5 Q06481
PDB IDs		2DYQ 2YSC	5JBT 5TPT 8RQ6
Enriched GO Terms of Interacting Partners?		Intracellular Signaling Cassette Response To Growth Factor Cellular Response To Growth Factor Stimulus Cellular Response To Epidermal Growth Factor Stimulus ERBB Signaling Pathway Response To Epidermal Growth Factor Epidermal Growth Factor Receptor Signaling Pathway Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction ERBB2-EGFR Signaling Pathway Transition Metal Ion Binding Platelet Alpha Granule Early Endosome Membrane Receptor Complex Positive Regulation Of Epithelial Cell Proliferation ERBB2 Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Perinuclear Region Of Cytoplasm Endosome Intracellular Signal Transduction Regulation Of Toll-like Receptor Signaling Pathway Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Phosphate Metabolic Process Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Protein Localization Receptor Localization To Synapse Transmembrane Receptor Protein Tyrosine Kinase Activity Regulation Of Epithelial Cell Proliferation Glial Cell Development Basal Plasma Membrane Positive Regulation Of Protein Localization To Plasma Membrane Signal Transduction Positive Regulation Of Intracellular Signal Transduction Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Regulation Of MiRNA Transcription Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Protein Localization Positive Regulation Of Protein Localization To Cell Periphery Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Multivesicular Body, Internal Vesicle Lumen 3-phosphoinositide-dependent Protein Kinase Activity Positive Regulation Of MAPK Cascade Serine-type Endopeptidase Inhibitor Activity Positive Regulation Of Protein Localization To Membrane Regulation Of MiRNA Metabolic Process Protein Kinase Activity Ruffle Membrane Regulation Of Cellular Localization	Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Negative Regulation Of Apoptotic Process Regulation Of Gene Expression Regulation Of Protein Localization Regulation Of Multicellular Organismal Process Signal Transduction Negative Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Cycle Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Biosynthetic Process Leading Edge Cell Differentiation Regulation Of Macromolecule Metabolic Process Positive Regulation Of Protein Localization Apoptotic Process Regulation Of RNA Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Peptidyl-threonine Phosphorylation Programmed Cell Death Cell Death Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Macromolecule Metabolic Process Low-density Lipoprotein Particle Receptor Binding Protein Localization To Site Of Double-strand Break Amyloid-beta Binding Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Establishment Of Protein Localization Negative Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Population Proliferation Regulation Of Metabolic Process Response To Lipid Response To Steroid Hormone Regulation Of Cell Adhesion Regulation Of Primary Metabolic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Intracellular Signaling Cassette Integrated Stress Response Signaling Transcription Factor AP-1 Complex Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Stress Positive Regulation Of Transcription By RNA Polymerase II
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?