DNAJA1 and TM4SF1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DNAJA1	TM4SF1
Description		DnaJ heat shock protein family (Hsp40) member A1	transmembrane 4 L six family member 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Endoplasmic Reticulum Cytosol Microtubule Cytoskeleton Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome Cytoplasmic Side Of Endoplasmic Reticulum Membrane	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Binding ATPase Activator Activity Protein Binding ATP Binding Zinc Ion Binding Hsp70 Protein Binding Tat Protein Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding Metal Ion Binding Low-density Lipoprotein Particle Receptor Binding Unfolded Protein Binding Protein-folding Chaperone Binding C3HC4-type RING Finger Domain Binding	Protein Binding
	Biological Process	Protein Folding Response To Unfolded Protein Response To Heat Negative Regulation Of Protein Ubiquitination Protein Refolding Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity Regulation Of Protein Transport Protein Localization To Mitochondrion Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Negative Regulation Of Nitrosative Stress-induced Intrinsic Apoptotic Signaling Pathway	Blastocyst Formation
Pathways		HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Mitochondrial unfolded protein response (UPRmt)
Drugs
Diseases
GWAS			Alanine aminotransferase levels ( 33547301)
Interacting Genes		30 interacting genes: ARL4D BCS1L BRCA1 CAV2 CD58 CDC16 CFTR CRBN DSCR9 ERG FZR1 HIVEP1 HMGCL HSPA8 HUNK LINC01554 LSM2 NELFCD NUDT3 OGT PAXIP1 PGR PTEN PTTG1 SNCA SUMO2 SUMO4 TM4SF1 TXN UBC	7 interacting genes: ANPEP DDR1 DNAJA1 HSPA8 SDCBP2 SLC13A1 TUBA4A
Entrez ID		3301	4071
HPRD ID		04159	01854
Ensembl ID		ENSG00000086061	ENSG00000169908
Uniprot IDs		B7Z5C0 P31689	F8WF27 P30408
PDB IDs		2LO1 2M6Y 6E8M 8E2O
Enriched GO Terms of Interacting Partners?		Protein Tag Activity Nucleus Enzyme Binding Negative Regulation Of Protein-containing Complex Assembly Anaphase-promoting Complex Binding Protein Modification By Small Protein Conjugation Ubiquitin Ligase Activator Activity	C3HC4-type RING Finger Domain Binding Extracellular Exosome ATPase Activator Activity MHC Class II Protein Complex Binding Protein Refolding Protein-macromolecule Adaptor Activity Alanyl Aminopeptidase Activity Protein Transport Into Plasma Membrane Raft Smooth Muscle Cell-matrix Adhesion Protein Tyrosine Kinase Collagen Receptor Activity Response To Unfolded Protein G Protein-coupled Receptor Binding Heat Shock Protein Binding Negative Regulation Of Nitrosative Stress-induced Intrinsic Apoptotic Signaling Pathway Enzyme Binding Chaperone-mediated Autophagy Translocation Complex Disassembly Lumenal Side Of Lysosomal Membrane Sodium:sulfate Symporter Activity Monoatomic Anion:sodium Symporter Activity Histone H3K9ac Reader Activity Histone H4K5ac Reader Activity Histone H4K8ac Reader Activity Histone H4K12ac Reader Activity Protein-folding Chaperone Binding Unfolded Protein Binding Regulation Of Protein Import Negative Regulation Of DNA Damage Checkpoint Histone H3K27ac Reader Activity Sodium Ion Transmembrane Transport Protein Transport Into Membrane Raft Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy P-TEFb Complex Binding Histone H4 Reader Activity Positive Regulation Of Potassium Ion Import Across Plasma Membrane Protein Localization To Plasma Membrane Raft Clathrin Coat Disassembly Histone H4K16ac Reader Activity Positive Regulation Of Sodium Ion Export Across Plasma Membrane P-type Sodium:potassium-exchanging Transporter Activity ATP Metabolic Process Sodium Ion Transport Regulation Of Potassium Ion Import Negative Regulation Of JUN Kinase Activity Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Chaperone-mediated Autophagy Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane ATP-dependent Protein Disaggregase Activity Vesicle Uncoating Secondary Active Sulfate Transmembrane Transporter Activity RNA Polymerase II C-terminal Domain Binding
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