AGFG2 and EPS15L1

Number of citations of the paper that reports this interaction (PubMedID 9303539)
48

Data Source:
BioGRID (genetic interference)
HPRD (in vitro)

		AGFG2	EPS15L1
Description		ArfGAP with FG repeats 2	epidermal growth factor receptor pathway substrate 15 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Membrane Cytoplasmic Vesicle	Nucleus Cytoplasm Cytosol Plasma Membrane Clathrin-coated Pit Membrane Clathrin Coat Of Coated Pit Presynapse
	Molecular Function	GTPase Activator Activity Zinc Ion Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Protein-macromolecule Adaptor Activity Cadherin Binding Metal Ion Binding
	Biological Process	Acrosome Assembly Spermatid Nucleus Differentiation Intermediate Filament Organization	Endocytosis Endosomal Transport Synaptic Vesicle Endocytosis
Pathways			EGFR downregulation Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Hematocrit ( 27863252) Subcortical volume (MOSTest) ( 32665545)	Basophil count ( 32888494) Body size at age 10 ( 32376654) Eosinophil count ( 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494) Lymphocyte count ( 32888494 27863252 29403010) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 22190364 31604244 24076602) Neutrophil percentage of granulocytes ( 27863252) Neutrophil percentage of white cells ( 27863252 32888494) White blood cell count ( 27863252 21738480 32888494) White matter integrity ( 23218918)
Interacting Genes		4 interacting genes: APP EPS15 EPS15L1 ITSN1	13 interacting genes: ABL1 AGFG1 AGFG2 EPN1 FCHO1 FCHO2 GNG5 LRRC7 SIM2 STON2 TRAPPC2 TRAPPC2B UBC
Entrez ID		3268	58513
HPRD ID		04932	09445
Ensembl ID		ENSG00000106351	ENSG00000127527
Uniprot IDs		A4D2D6 O95081	A0AAQ5BI61 Q9UBC2
PDB IDs
Enriched GO Terms of Interacting Partners?		Clathrin-coated Pit Endocytosis Vesicle-mediated Transport In Synapse Clathrin Coat Of Coated Pit Import Into Cell Postsynaptic Endocytic Zone Protein-macromolecule Adaptor Activity Endosomal Transport Intracellular Transport Vesicle-mediated Transport Synaptic Vesicle Endocytosis Presynaptic Endocytosis Cellular Localization Establishment Of Localization In Cell Calcium Ion Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Endosome Acetylcholine Receptor Activator Activity Recycling Endosome Regulation Of Postsynapse Organization Lipoprotein Particle Positive Regulation Of Protein Import Dendritic Spine Clathrin-dependent Synaptic Vesicle Endocytosis PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Synapse Receptor-mediated Endocytosis Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Early Endosome Membrane Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Caveolin-mediated Endocytosis Presynapse Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition	Vesicle-mediated Transport Clathrin-dependent Endocytosis Endocytosis Spermatid Nucleus Differentiation Clathrin-coated Pit TRAPPII Protein Complex TRAPPIII Protein Complex Establishment Of Localization In Cell Import Into Cell TRAPP Complex Vesicle Organization Clathrin Coat Assembly COPII Vesicle Coating Acrosome Assembly Vesicle Tethering Receptor-mediated Endocytosis Vesicle Coating Synaptic Vesicle Endocytosis Presynaptic Endocytosis Protein Localization To Cytoplasmic Microtubule Plus-end Cellular Component Assembly Secretory Granule Organization Transitional One Stage B Cell Differentiation Podocyte Apoptotic Process DN4 Thymocyte Differentiation Phospholipase C-inhibiting G Protein-coupled Receptor Signaling Pathway Protein-containing Complex Assembly Cytoplasm Intermediate Filament Organization Endoplasmic Reticulum-Golgi Intermediate Compartment Clathrin-coated Vesicle Nicotinate-nucleotide Adenylyltransferase Activity Protein Localization To Microtubule Plus-end Intermediate Filament Cytoskeleton Organization Nucleus Organization Intermediate Filament-based Process Vesicle-mediated Transport In Synapse Protein-containing Complex Organization Microspike Assembly B-1 B Cell Homeostasis T Cell Receptor Signaling Pathway Positive Regulation Of Establishment Of T Cell Polarity Neuropilin Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?